Evidence map›Paper›PMID 29179870›Full record

ArticlePapillomavirus research (Amsterdam, Netherlands)2017

Cutaneous HPV and alpha-mucosal 9-valent HPV sero-status associations.

Shams Rahman, Anna R Giuliano, Dana E Rollison, Michael Pawlita, Tim Waterboer, Luisa L Villa, Eduardo Lazcano Ponce

Abstract read
In one paragraph

Article in Papillomavirus research (Amsterdam, Netherlands), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shams RahmanPetrock College of Health Sciences, Bethune-Cookman University, Daytona Beach, USA.
Anna R GiulianoCenter for Infection Research in Cancer, Moffitt Cancer Center, Tampa, USA. Electronic address: anna.giuliano@moffitt.org.
Dana E RollisonCenter for Infection Research in Cancer, Moffitt Cancer Center, Tampa, USA.
Michael PawlitaInfection, Inflammation and Cancer Research Program, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Tim WaterboerInfection, Inflammation and Cancer Research Program, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Luisa L VillaSchool of Medicine, University of São Paulo, São Paulo, Brazil.
Eduardo Lazcano PonceInstituto Nacional de Salud Publica, Cuernavaca, Mexico.

Funding

Natural History of HPV Infection in Men: The HIM StudyR01CA098803 · NCI · H. LEE MOFFITT CANCER CTR &RES INST · PI GIULIANO, ANNA R. · 2004 to 2014
$18.2M
Cutaneous Human Papillomavirus Infection and Risk of Incident External Genital LeR03CA176743 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI GIULIANO, ANNA R. · 2013 to 2014
$166k
NCI NIH HHS R01 CA098803NCI NIH HHS R03 CA176743
6 · The paper itself

Abstract

Seroepidemiology of human papillomaviruses (HPV) among men is poorly understood. We examined the association between seropositivity to cutaneous HPV and 9-valent HPV (9vHPV) types. Six hundred men were randomly selected from the HPV Infection in Men (HIM) Study. Archived serum specimens were tested for antibodies against 9vHPV types [low-risk (6/11) and high-risk (16/18/31/33/45/52/58)], and 14 cutaneous types, including β-types 5/8/12/14/17/22/23/24/38/47, α-type-27, γ-type-4, µ-type-1, and ν-type-41, using a GST L1-based multiplex serology assay. Risk factor data were collected through questionnaires. Logistic regression was used to evaluate associations between mucosal and cutaneous HPV types. Approximately 21% of men were positive for ≥ 1 cutaneous HPV type, and ≥ 1 nine-valent HPV vaccine type at the same time. Men who were seropositive for any-cutaneous HPV were nearly twice as likely to be seropositive for 9vHPV (adjusted odds ratio (AOR) = 1.97, 95% confidence interval (CI): 1.30-2.99), high-risk (AOR = 1.83; 95% CI: 1.04-3.20), low-risk (AOR = 1.92; 95% CI: 1.16-3.18), and four-valent, 4vHPV, (AOR = 2.01; 95% CI: 1.25-3.21). Type-specific cutaneous HPV seropositivity (types: 8/14/17/23/38/27/4/1) was also positively associated with seropositivity to 9vHPV, high-risk, and low-risk categories. These data indicate that exposure to cutaneous HPV and 9vHPV types is common. Future longitudinal studies are needed to assess the temporality of these associations.

Indexed as

AdolescentAdultAgedAntibodies, ViralBetapapillomavirusHumansLogistic ModelsMaleMiddle AgedMucous MembraneMupapillomavirusPapillomavirus InfectionsPapillomavirus VaccinesRisk FactorsSeroepidemiologic StudiesSerologic TestsAntibodies, ViralPapillomavirus Vaccines9-valent HPV vaccine typesCutaneous HPVHIM studyHPVSeroepidemiology

Identifiers

PMID29179870
PMCPMC5728424

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.