Evidence map›Paper›PMID 29179788›Full record

ReviewParasitology2018

X-ray micro-computed tomography (μCT): an emerging opportunity in parasite imaging.

James D B O'Sullivan, Julia Behnsen, Tobias Starborg, Andrew S MacDonald, Alexander T Phythian-Adams, Kathryn J Else, Sheena M Cruickshank, Philip J Withers

Abstract readReview
In one paragraph

Review in Parasitology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Review
  3. Exploring the anatomy ofInternational journal for parasitology. Parasites and wildlife · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Taking a microscale look at symbiotic interactions-and why it matters.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  11. Parasitology · 2021
    Article
  12. Review
  13. Whipworm and roundworm infections.Nature reviews. Disease primers · 2020
    Review
  14. Article
  15. Review
  16. Identification of genetic variations inThe Journal of international medical research · 2019
    Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

James D B O'SullivanSchool of Materials,The University of Manchester,Oxford Road,Manchester M13 9PL,UK.ORCID 0000-0002-7955-828X
Julia BehnsenSchool of Materials,The University of Manchester,Oxford Road,Manchester M13 9PL,UK.
Tobias StarborgSchool of Biological Sciences,The University of Manchester,Oxford Road,Manchester M13 9PL,UK.
Andrew S MacDonaldSchool of Biological Sciences,The University of Manchester,Oxford Road,Manchester M13 9PL,UK.
Alexander T Phythian-AdamsSchool of Biological Sciences,The University of Manchester,Oxford Road,Manchester M13 9PL,UK.
Kathryn J ElseSchool of Biological Sciences,The University of Manchester,Oxford Road,Manchester M13 9PL,UK.
Sheena M CruickshankSchool of Biological Sciences,The University of Manchester,Oxford Road,Manchester M13 9PL,UK.
Philip J WithersSchool of Materials,The University of Manchester,Oxford Road,Manchester M13 9PL,UK.

Funding

Medical Research Council MR/N022661/1
6 · The paper itself

Abstract

X-ray micro-computed tomography (μCT) is a technique which can obtain three-dimensional images of a sample, including its internal structure, without the need for destructive sectioning. Here, we review the capability of the technique and examine its potential to provide novel insights into the lifestyles of parasites embedded within host tissue. The current capabilities and limitations of the technology in producing contrast in soft tissues are discussed, as well as the potential solutions for parasitologists looking to apply this technique. We present example images of the mouse whipworm Trichuris muris and discuss the application of μCT to provide unique insights into parasite behaviour and pathology, which are inaccessible to other imaging modalities.

Indexed as

Imaging, Three-DimensionalX-Ray MicrotomographyAnimalsMiceParasitesTrichuriasisTrichurisHelminthmicroscopypathologyX-ray tomography

Identifiers

PMID29179788
PMCPMC6088774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.