Observational studyScandinavian journal of trauma, resuscitation and emergency medicine2017
Routine blood tests are associated with short term mortality and can improve emergency department triage: a cohort study of >12,000 patients.
Observational study in Scandinavian journal of trauma, resuscitation and emergency medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Trial
- Availability of suPAR in emergency departments may improve risk stratification: a secondary analysis of the TRIAGE III trial.Scandinavian journal of trauma, resuscitation and emergency medicine · 2019Trial
- Routine laboratory data for predicting 30-day emergency department revisits: the AXIS-2 risk score.BMC emergency medicine · 2026Article
- A tool based on objective data to identify patients at elevated risk of hospital-onsetAntimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- New machine-learning models outperform conventional risk assessment tools in Gastrointestinal bleeding.Scientific reports · 2025Article
- Platelet-white cell ratio is more strongly associated with mortality than other common risk ratios derived from complete blood counts.Nature communications · 2025Article
- Article
- Benefits of emergency department routine blood test performance on patients whose allocated triage category is not time critical: a retrospective study.BMC health services research · 2024Observational
- Predicting Short-Term Mortality in Older Patients Discharged from Acute Hospitalizations Lasting Less Than 24 Hours.Clinical epidemiology · 2023Article
- Age-adjusted interpretation of biomarkers of renal function and homeostasis, inflammation, and circulation in Emergency Department patients.Scientific reports · 2022Observational
- Use of Multiprognostic Index Domain Scores, Clinical Data, and Machine Learning to Improve 12-Month Mortality Risk Prediction in Older Hospitalized Patients: Prospective Cohort Study.Journal of medical Internet research · 2021Article
- Disposition Decision Support by Laboratory Based Outcome Prediction.Journal of clinical medicine · 2021Article
- Rapid triage for COVID-19 using routine clinical data for patients attending hospital: development and prospective validation of an artificial intelligence screening test.The Lancet. Digital health · 2021Article
- The selection of indicators from initial blood routine test results to improve the accuracy of early prediction of COVID-19 severity.PloS one · 2021Article
- Predicting Adverse Outcomes for Febrile Patients in the Emergency Department Using Sparse Laboratory Data: Development of a Time Adaptive Model.JMIR medical informatics · 2020Article
- Predicting 30-day mortality using point-of-care testing; an external validation and derivation study.PloS one · 2020Article
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrioritization of acutely ill patients in the Emergency Department remains a challenge. We aimed to evaluate whether routine blood tests can predict mortality in unselected patients in an emergency department and to compare risk prediction with a formalized triage algorithm.
methodsA prospective observational cohort study of 12,661 consecutive admissions to the Emergency Department of Nordsjælland University Hospital during two separate periods in 2010 (primary cohort, n = 6279) and 2013 (validation cohort, n = 6383). Patients were triaged in five categories by a formalized triage algorithm. All patients with a full routine biochemical screening (albumin, creatinine, c-reactive protein, haemoglobin, lactate dehydrogenase, leukocyte count, potassium, and sodium) taken at triage were included. Information about vital status was collected from the Danish Central Office of Civil registration. Multiple logistic regressions were used to predict 30-day mortality. Validation was performed by applying the regression models on the 2013 validation cohort.
resultsThirty-day mortality was 5.3%. The routine blood tests had a significantly stronger discriminative value on 30-day mortality compared to the formalized triage (AUC 88.1 [85.7;90.5] vs. 63.4 [59.1;67.5], p < 0.01). Risk stratification by routine blood tests was able to identify a larger number of low risk patients (n = 2100, 30-day mortality 0.1% [95% CI 0.0;0.3%]) compared to formalized triage (n = 1591, 2.8% [95% CI 2.0;3.6%]), p < 0.01.
conclusionsRoutine blood tests were strongly associated with 30-day mortality in acutely ill patients and discriminatory ability was significantly higher than with a formalized triage algorithm. Thus routine blood tests allowed an improved risk stratification of patients presenting in an emergency department.
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