Evidence map›Paper›PMID 29179734›Full record

Trial reportTrials2017

An integrated digital/clinical approach to smoking cessation in lung cancer screening: study protocol for a randomized controlled trial.

Amanda L Graham, Michael V Burke, Megan A Jacobs, Sarah Cha, Ivana T Croghan, Darrell R Schroeder, James P Moriarty, Bijan J Borah, Donna F Rasmussen, M Jody Brookover and 3 more

Registry-linked trialOpen access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03084835 (Smoking Cessation in Lung Cancer Screening), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03084835 naterminatednot on this map

Smoking Cessation in Lung Cancer Screening: Integrated Digital/Clinical Approach

TypeinterventionalSponsorMayo ClinicRan2017 to 2019Enrolled32ConditionsSmokingArmsUsual Care, WEB+TXT, WEB+TXT+TTS
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Article
  3. Potential Impact of Cessation Interventions at the Point of Lung Cancer Screening on Lung Cancer and Overall Mortality in the United States.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2020
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Amanda L GrahamSchroeder Institute for Tobacco Research and Policy Studies at Truth Initiative, 900 G Street NW, 4th Floor, Washington, DC, 20001, USA. agraham@truthinitiative.org.
Michael V BurkeMayo Clinic Nicotine Dependence Center, Mayo Clinic, Rochester, MN, USA.
Megan A JacobsSchroeder Institute for Tobacco Research and Policy Studies at Truth Initiative, 900 G Street NW, 4th Floor, Washington, DC, 20001, USA.
Sarah ChaSchroeder Institute for Tobacco Research and Policy Studies at Truth Initiative, 900 G Street NW, 4th Floor, Washington, DC, 20001, USA.
Ivana T CroghanMayo Clinic Nicotine Dependence Center, Mayo Clinic, Rochester, MN, USA.
Darrell R SchroederDivision of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
James P MoriartyKern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA.
Bijan J BorahDivision of Health Care Policy and Research, Mayo Clinic, Rochester, MN, USA.
Donna F RasmussenMayo Clinic Nicotine Dependence Center, Mayo Clinic, Rochester, MN, USA.
M Jody BrookoverSchroeder Institute for Tobacco Research and Policy Studies at Truth Initiative, 900 G Street NW, 4th Floor, Washington, DC, 20001, USA.
Dale B SuesseDivision of Research and Education Systems Support, Mayo Clinic, Rochester, MN, USA.
David E MidthunDivision of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA.
J Taylor HaysMayo Clinic Nicotine Dependence Center, Mayo Clinic, Rochester, MN, USA.
Mayo Clinic in Florida · USAmerican Legacy Foundation · USMayo Clinic · USMayo Clinic in Arizona · US

Funding

Smoking cessation in lung cancer screening: integrated digital/clinical approachR01CA207048 · NCI · MAYO CLINIC ROCHESTER · PI HAYS, J TAYLOR, MIDTHUN, DAVID E · 2016 to 2017
$1.2M
National Cancer Institute R01CA207048NCI NIH HHS R01 CA207048
6 · The paper itself

Abstract

backgroundDelivering effective tobacco dependence treatment that is feasible within lung cancer screening (LCS) programs is crucial for realizing the health benefits and cost savings of screening. Large-scale trials and systematic reviews have demonstrated that digital cessation interventions (i.e. web-based and text message) are effective, sustainable over the long-term, scalable, and cost-efficient. Use of digital technologies is commonplace among older adults, making this a feasible approach within LCS programs. Use of cessation treatment has been improved with models that proactively connect smokers to treatment rather than passive referrals. Proactive referral to cessation treatment has been advanced through healthcare systems changes such as modifying the electronic health record to automatically link smokers to treatment.

methodsThis study evaluates the impact of a proactive enrollment strategy that links LCS-eligible smokers with an evidence-based intervention comprised of a web-based (WEB) program and integrated text messaging (TXT) in a three-arm randomized trial with repeated measures at one, three, six, and 12 months post randomization. The primary outcome is biochemically confirmed abstinence at 12 months post randomization. We will randomize 1650 smokers who present for a clinical LCS to: (1) a usual care control condition (UC) which consists of Ask-Advise-Refer; (2) a digital (WEB + TXT) cessation intervention; or (3) a digital cessation intervention combined with tobacco treatment specialist (TTS) counseling (WEB + TXT + TTS). DISCUSSION: The scalability and sustainability of a digital intervention may represent the most cost-effective and feasible approach for LCS programs to proactively engage large numbers of smokers in effective cessation treatment. We will also evaluate the impact and cost-effectiveness of adding proven clinical intervention provided by a TTS. We expect that a combined digital/clinical intervention will yield higher quit rates than digital alone, but that it may not be as cost-effective or feasible for LCS programs to implement. This study is innovative in its use of interoperable, digital technologies to deliver a sustainable, scalable, high-impact cessation intervention and to facilitate its integration within clinical practice. It will add to the growing knowledge base about the overall effectiveness of digital interventions and their role in the healthcare delivery system.

trial registrationClinicalTrials.gov, NCT03084835 . Registered on 9 March 2017.

Indexed as

CounselingText MessagingTherapy, Computer-AssistedTomography, X-Ray ComputedAgedAged, 80 and overClinical ProtocolsDelivery of Health Care, IntegratedEarly Detection of CancerFemaleHumansInternetLung NeoplasmsMaleMiddle AgedPredictive Value of TestsCancer screeningCounselingInternetLung cancerSmoking cessationText messagesTobacco use cessation

Identifiers

PMID29179734
PMCPMC5704639
OpenAlexW2768558761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.