Evidence map›Paper›PMID 29179723›Full record

ReviewJournal of neuroinflammation2017

Novel pathomechanisms in inflammatory neuropathies.

David Schafflick, Bernd C Kieseier, Heinz Wiendl, Gerd Meyer Zu Horste

Abstract readReview
In one paragraph

Review in Journal of neuroinflammation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Autoantibody screening in Guillain-Barré syndrome.Journal of neuroinflammation · 2021
    Observational
  9. Novel Immunological and Therapeutic Insights in Guillain-Barré Syndrome and CIDP.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Cladribine repurposed in multiple sclerosis: making a fortune out of a generic drug.European journal of hospital pharmacy : science and practice · 2019
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

David SchafflickDepartment of Neurology, Westfälische Wilhems-University, Albert-Schweitzer-Campus 1, 48149, Münster, Germany.
Bernd C KieseierDepartment of Neurology, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.
Heinz WiendlDepartment of Neurology, Westfälische Wilhems-University, Albert-Schweitzer-Campus 1, 48149, Münster, Germany.
Gerd Meyer Zu HorsteDepartment of Neurology, Westfälische Wilhems-University, Albert-Schweitzer-Campus 1, 48149, Münster, Germany. gerd.mzh@uni-muenster.de.ORCID http://orcid.org/0000-0002-4341-4719

Funding

Deutsche Forschungsgemeinschaft ME4050/4-1
6 · The paper itself

Abstract

Inflammatory neuropathies are rare autoimmune-mediated disorders affecting the peripheral nervous system. Considerable progress has recently been made in understanding pathomechanisms of these disorders which will be essential for developing novel diagnostic and therapeutic strategies in the future. Here, we summarize our current understanding of antigenic targets and the relevance of new immunological concepts for inflammatory neuropathies. In addition, we provide an overview of available animal models of acute and chronic variants and how new diagnostic tools such as magnetic resonance imaging and novel therapeutic candidates will benefit patients with inflammatory neuropathies in the future. This review thus illustrates the gap between pre-clinical and clinical findings and aims to outline future directions of development.

Indexed as

AnimalsGuillain-Barre SyndromeHumansPolyradiculoneuropathy, Chronic Inflammatory DemyelinatingAnimal modelChronic inflammatory demyelinating polyneuropathyExperimental autoimmune neuritisGuillain-Barré syndromeTh17 cells

Identifiers

PMID29179723
PMCPMC5704548

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.