ArticleBMC medicine2017
Depression comorbid with tuberculosis and its impact on health status: cross-sectional analysis of community-based data from 48 low- and middle-income countries.
Article in BMC medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 6 of them syntheses that pooled it.
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Who cites it
67 citing papers in PubMed, 6 syntheses or guidelines pooled it, 133 citations in OpenAlex.
- Pooled it
- Review: missed tuberculosis cases in India: a systematic analysis of diagnostic, treatment, and reporting gaps.BMC health services research · 2025Pooled it
- Prevalence of depression in people with tuberculosis in East Africa: a systematic review and meta-analysis.African health sciences · 2023Pooled it
- Physical activity and visual difficulties in 36 low- and middle-income countries.Eye (London, England) · 2022Pooled it
- The relationship between mental health and risk of active tuberculosis: a systematic review.BMJ open · 2022Pooled it
- Pharmacological or non-pharmacological interventions for treatment of common mental disorders associated with Tuberculosis: A systematic review.Chronic respiratory diseasePooled it
- Qualitative study of patient experiences of mental distress during TB investigation and treatment in Zambia.BMC psychology · 2022Trial
- Challenges and countermeasures of the "Xinjiang Model" in tuberculosis prevention and control: a qualitative study based on health specialists' perspectives.BMC public health · 2026Article
- Depressive Symptoms in Pediatric Tuberculosis: A Retrospective Two-Time-Point Observational Study.Diseases (Basel, Switzerland) · 2026Article
- Facilitating and Hindering Factors in Discharge Preparation During the Hospital-to-Home Transition Period for Newly Diagnosed Tuberculosis Patients: A Qualitative Study.Patient preference and adherence · 2026Article
- Prevalence and predictors of depression in tuberculosis patients in india: a systematic review and meta-analysis.Discover mental health · 2025Review
- Factors Associated with Mental Health Problems Among Tuberculosis Patients Attending Tertiary Care Hospitals in the Bangkok Metropolitan Region, Thailand: A Hospital-Based Survey.Clinics and practice · 2025Article
- Can greenspace modify the combined effects of multiple air pollutants on pulmonary tuberculosis treatment outcomes? An empirical study conducted in Zhejiang Province, China.Environmental health and preventive medicine · 2025Article
- Facilitators and barriers for completion of the diagnostic process among people with presumed tuberculosis in Central Uganda.PLOS global public health · 2025Article
- Review
- Risk Factors for the Occurrence of Depressive Disorders in Pediatric Patients With Tuberculosis.Pediatric health, medicine and therapeutics · 2025Article
- Dual burden of TB and mental ill-health: Prevalence and associated factors of anxiety and depression among TB patients in Gujarat.Journal of family medicine and primary care · 2024Article
- Dynapenic abdominal obesity and activities of daily living disability among older adults residing in low- and middle-income countries.Aging clinical and experimental research · 2024Article
- Article
- Stigma, depression, and quality of life among people with pulmonary tuberculosis diagnosed through active and passive case finding in Nepal: a prospective cohort study.BMC global and public health · 2024Article
7 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 8 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDepression in tuberculosis increases the risk for adverse health outcomes. However, little is known about comorbid depression and tuberculosis in the general population. Thus, we assessed the association between depression and tuberculosis, and the decrements in health status associated with this comorbidity in 48 low- and middle-income countries.
methodsCross-sectional, community-based data from the World Health Survey on 242,952 individuals aged ≥ 18 years were analyzed. Based on the World Mental Health Survey version of the Composite International Diagnostic Interview, past 12-month depression was categorized into depressive episode, brief depressive episode, subsyndromal depression, and no depression. Health status across six domains (cognition, interpersonal activities, sleep/energy, self-care, mobility, pain/discomfort) was assessed. Multivariable logistic and linear regression analyses were performed to assess the associations.
resultsThe prevalence of depressive episode among those with and without tuberculosis was 23.7% and 6.8%, respectively (P < 0.001). Tuberculosis was associated with a 1.98 (95% CI 1.47-2.67), 1.75 (95% CI 1.26-2.42), and 3.68 (95% CI 3.01-4.50) times higher odds for subsyndromal depression, brief depressive episode, and depressive episode, respectively. Depressive episode co-occurring with tuberculosis was associated with significantly worse health status across all six domains compared to tuberculosis alone. Interaction analysis showed that depression significantly amplifies the association between TB and difficulties in self-care but not in other health domains.
conclusionsDepression is highly prevalent in adults with tuberculosis, and is associated with worse health status compared to tuberculosis without depression. Public health efforts directed to the recognition and management of depression in people with tuberculosis may lead to better outcomes.
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