Evidence map›Paper›PMID 29179705›Full record

SynthesisBMC ophthalmology2017

Vitrectomy with internal limiting membrane peeling versus inverted internal limiting membrane flap technique for macular hole-induced retinal detachment: a systematic review of literature and meta-analysis.

Jing Yuan, Ling-Lin Zhang, Yu-Jie Lu, Meng-Yao Han, Ai-Hua Yu, Xiao-Jun Cai

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Platelet concentrates in macular hole surgery. A journey through the labyrinth of terminology, preparation, and application: a comprehensive review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Review
  9. Management of Myopic Maculopathy: A Review.Turkish journal of ophthalmology · 2023
    Review
  10. Article
  11. Review
  12. Update on surgical management of complex macular holes: a review.International journal of retina and vitreous · 2021
    Review
  13. Article
  14. Inverted internal limiting membrane flap technique in eyes with large idiopathic full-thickness macular hole: long-term functional and morphological outcomes.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Article
  15. Article
  16. [Biomarkers in full-thickness and lamellar defects of the macula].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2021
    Review
  17. Article
  18. Review
  19. Novel use of Finesse Flex loop for macular hole retinal detachment.American journal of ophthalmology case reports · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jing YuanDepartment of Ophthalmology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, People's Republic of China.
Ling-Lin ZhangDepartment of Ophthalmology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, People's Republic of China.
Yu-Jie LuDepartment of Ophthalmology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, People's Republic of China.
Meng-Yao HanDepartment of Ophthalmology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, People's Republic of China.
Ai-Hua YuDepartment of Ophthalmology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, People's Republic of China.
Xiao-Jun CaiDepartment of Ophthalmology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, People's Republic of China. xiaojuncai168@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the effects on vitrectomy with internal limiting membrane (ILM) peeling versus vitrectomy with inverted internal limiting membrane flap technique for macular hole-induced retinal detachment (MHRD).

methodsPubmed, Cochrane Library, and Embase were systematically searched for studies that compared ILM peeling with inverted ILM flap technique for macular hole-induced retinal detachment. The primary outcomes are the rate of retinal reattachment and the rate of macular hole closure 6 months later after initial surgery, the secondary outcome is the postoperative best-corrected visual acuity (BCVA) 6 months later after initial surgery.

resultsFour studies that included 98 eyes were selected. All the included studies were retrospective comparative studies. The preoperative best-corrected visual acuity was equal between ILM peeling and inverted ILM flap technique groups. It was indicated that the rate of retinal reattachment (odds ratio (OR) = 0.14, 95% confidence interval (CI):0.03 to 0.69; P = 0.02) and macular hole closure (OR = 0.06, 95% CI:0.02 to 0.19; P < 0.00001) after initial surgery was higher in the group of vitrectomy with inverted ILM flap technique than that in the group of vitrectomy with ILM peeling. However, there was no statistically significant difference in postoperative best-corrected visual acuity (mean difference (MD) 0.18 logarithm of the minimum angle of resolution; 95% CI -0.06 to 0.43 ; P = 0.14) between the two surgery groups.

conclusionCompared with ILM peeling, vitrectomy with inverted ILM flap technique resulted significantly higher of the rate of retinal reattachment and macular hole closure, but seemed does not improve postoperative best-corrected visual acuity.

Indexed as

Surgical FlapsEpiretinal MembraneHumansRetinal DetachmentRetinal PerforationsRetrospective StudiesVitrectomyInternal limiting membrane peelingInverted internal limiting membrane flap techniqueMacular hole-induced retinal detachmentMeta-analysisVitrectomy

Identifiers

PMID29179705
PMCPMC5704533

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.