Evidence map›Paper›PMID 29179622›Full record

ArticleJournal of neurotrauma2018

Traumatic Brain Injury Impairs Myogenic Constriction of Cerebral Arteries: Role of Mitochondria-Derived H

Nikolett Szarka, Mallikarjuna R Pabbidi, Krisztina Amrein, Endre Czeiter, Gergely Berta, Krisztina Pohoczky, Zsuzsanna Helyes, Zoltan Ungvari, Akos Koller, Andras Buki and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurotrauma, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
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  8. Astrocytic TRPV4 Channels and Their Role in Brain Ischemia.International journal of molecular sciences · 2023
    Review
  9. Article
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  11. Review
  12. Article
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  15. Review
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  18. Article
  19. Channels that Cooperate with TRPV4 in the Brain.Journal of molecular neuroscience : MN · 2020
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Nikolett SzarkaCerebrovascular Laboratory, Department of Neurosurgery, Medical School University of Pecs, Pecs. Hungary.
Mallikarjuna R PabbidiDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Krisztina AmreinCerebrovascular Laboratory, Department of Neurosurgery, Medical School University of Pecs, Pecs. Hungary.
Endre CzeiterCerebrovascular Laboratory, Department of Neurosurgery, Medical School University of Pecs, Pecs. Hungary.
Gergely BertaDepartment of Medical Biology, Medical School University of Pecs, Pecs. Hungary.
Krisztina PohoczkyDepartment of Pharmacology and Pharmacotherapy, Medical School University of Pecs, Pecs. Hungary.
Zsuzsanna HelyesDepartment of Pharmacology and Pharmacotherapy, Medical School University of Pecs, Pecs. Hungary.
Zoltan UngvariReynolds Oklahoma Center on Aging, Donald W. Reynolds Department of Geriatric Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
Akos KollerCerebrovascular Laboratory, Department of Neurosurgery, Medical School University of Pecs, Pecs. Hungary.
Andras BukiCerebrovascular Laboratory, Department of Neurosurgery, Medical School University of Pecs, Pecs. Hungary.
Peter TothCerebrovascular Laboratory, Department of Neurosurgery, Medical School University of Pecs, Pecs. Hungary.
University of Oklahoma Health Sciences Center · USUniversity of Pecs · HUNew York Medical College · USUniversity of Mississippi Medical Center · US

Funding

Radiation-induced astrocyte dysfunction and cognitive declineR01NS100782 · NINDS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI UNGVARI, ZOLTAN ISTVAN · 2018 to 2022
$1.7M
NINDS NIH HHS R01 NS100782
6 · The paper itself

Abstract

Traumatic brain injury (TBI) impairs autoregulation of cerebral blood flow, which contributes to the development of secondary brain injury, increasing mortality of patients. Impairment of pressure-induced myogenic constriction of cerebral arteries plays a critical role in autoregulatory dysfunction; however, the underlying cellular and molecular mechanisms are not well understood. To determine the role of mitochondria-derived H

Indexed as

autoregulationintracranial hypertensionoxidative stresssecondary injury

Identifiers

PMID29179622
PMCPMC5865628
OpenAlexW2770727372

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.