ArticleOncotarget2017
Ischemic stroke in patients with POEMS syndrome: a case report and comprehensive analysis of literature.
Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- Autoimmune Encephalitis in a Patient with a Solitary Intracranial Plasmacytoma.Internal medicine (Tokyo, Japan) · 2024Article
- Acute leukoencephalopathy associated with daratumumab treatment in POEMS syndrome: a case report.Frontiers in immunology · 2024Article
- Surgical revascularization for quasi-moyamoya disease associated with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome: a case report and literature review.Nagoya journal of medical science · 2023Review
- Article
- Moyamoya Disease-like Cerebrovascular Stenotic Lesions Are an Important Phenotype of POEMS Syndrome-associated Vasculopathy.Internal medicine (Tokyo, Japan) · 2022Article
- Cerebrovascular manifestations in hematological diseases: an update.Journal of neurology · 2021Article
- Cerebral large artery stenosis and occlusion in POEMS syndrome.BMC neurology · 2021Article
- Ischemic stroke in patients with POEMS syndrome.Blood advances · 2020Article
- Irreversible Vasculopathy Proceeds Rapidly in POEMS Syndrome.Internal medicine (Tokyo, Japan) · 2019Article
- POEMS syndrome complicated by ischaemic stroke and cerebral vasculitis.BMJ case reports · 2019Article
- Characteristics of 1946 Cases of POEMS Syndrome in Chinese Subjects: A Literature-Based Study.Frontiers in immunology · 2019Review
- An update on the diagnosis and management of the polyneuropathy of POEMS syndrome.Journal of neurology · 2019Review
- Atypical central retinal artery occlusion as the first presentation of POEMS syndrome: a case report.BMC neurology · 2018Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPOEMS syndrome is a rare multi-systemic disease characterized by polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes. Arterial or venous thrombosis is a less-common complication of POEMS syndrome. Ischemic stroke has also been reported sporadically. However, the association between POEMS syndrome and ischemic stroke has not been entirely understood.
methodsA case of ischemic stroke caused by cerebral vasculitis in a patient with POEMS syndrome was presented. Then a comprehensive review and analysis of the literature were performed.
resultsA total of 28 patients were identified. The common clinical manifestations of POEMS syndrome were rather non-specific in patients with ischemic stroke compared with those of patients without ischemic stroke. Twenty patients were found with multiple ischemic lesions (71.5%). In the 25 patients who had undergone the evaluation of cerebral arteries, nineteen patients (76.0%) were found with cerebral vasculopathy. Twelve patients (48.0%) had more than one cerebral artery involved. Ischemic events were documented in 8 patients even when they were undergoing all the therapy for ischemic stroke. Ten (55.6%) of the 18 patients who had survival data died within two years after stroke events.
conclusionComprehensive analysis of literature revealed several trends in patients with ischemic stroke and POEMS syndrome including a low survival rate and a preponderance of cerebral vasculopathy and multiple cerebral arteries affected. Ischemic stroke may be a poor outcome predictor in patients with POEMS syndrome. Further researches focusing on a larger cohort may help in better characterizing and treating this rare complication of POEMS syndrome.
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