Evidence map›Paper›PMID 29179456›Full record

ArticleOncotarget2017

Combined Ki67 and ERCC1 for prognosis in non-keratinizing nasopharyngeal carcinoma underwent chemoradiotherapy.

Ying Lu, Haixin Huang, Min Kang, Min Yi, Hui Yang, Sibei Wu, Rensheng Wang

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. A multimodal approach for establishingFrontiers in pharmacology · 2025
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ying LuDepartment of Oncology, Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou, Gaungxi 545000, China.
Haixin HuangDepartment of Oncology, Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou, Gaungxi 545000, China.
Min KangDepartment of Radiation Oncology, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China.
Min YiDepartment of Pathology, Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou, Gaungxi 545000, China.
Hui YangDepartment of Oncology, Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou, Gaungxi 545000, China.
Sibei WuDepartment of Oncology, Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou, Gaungxi 545000, China.
Rensheng WangDepartment of Radiation Oncology, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China.
Fourth Affiliated Hospital of Guangxi Medical University · CNFirst Affiliated Hospital of GuangXi Medical University · CNGuangxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to assess the predictive value of combined Ki67 and ERCC1 in distant metastasis-free nasopharyngeal carcinoma. 334 such cases were retrospectively assessed. Immunohistochemistry was used to evaluate Ki67 and ERCC1 protein levels in tumor tissues. Associations of Ki67 and ERCC1 amounts with clinical characteristics and survival were analyzed. Medium follow-up was 48.7 months; overall survival (OS), disease-free survival (DFS), distant metastasis-free survival (DMFS), and local recurrence-free survival (LRFS) were 91.3%, 76.0%, 82.0%, and 91.9%, respectively. High Ki67 expression was found in 35.6% patients, and positively correlated with clinical- and N- staging (

Indexed as

ERCC1Ki67nasopharyngeal carcinomaprognosis

Identifiers

PMID29179456
PMCPMC5687626
OpenAlexW2734372898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.