ArticleAddictive behaviors2018
Patterns of adverse childhood experiences and substance use among young adults: A latent class analysis.
Article in Addictive behaviors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04678960 (Preventing Opioid Use Among Justice-involved Youth as They Transition to Adulthood), which is not on this map. Cited by 115 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Preventing Opioid Use Among Justice-involved Youth as They Transition to Adulthood: Leveraging Safe Adults (LeSA)
Who cites it
115 citing papers in PubMed, 2 syntheses or guidelines pooled it, 246 citations in OpenAlex.
- Understanding adverse childhood experiences within the first decade of the ABCD study: A systematic review.Developmental cognitive neuroscience · 2026Pooled it
- Adverse childhood experiences and substance misuse in young people in India: results from the multisite cVEDA cohort.BMC public health · 2021Pooled it
- Preventing opioid use among justice-involved youth as they transition to adulthood: leveraging safe adults (LeSA).BMC public health · 2021Trial
- The Differential Impact of Emotional Support on Social Problem-Solving and Mental Health Among Latina Immigrant Survivors of Adverse Childhood Experiences.Research in nursing & health · 2026Article
- Strengths-Based Programs for Youth at Risk for Toxic Stress: A Scoping Review of Programs Targeting Mental Health, Substance Use, Parenting Skills, and Family Functioning.Trauma, violence & abuse · 2026Article
- Longitudinal patterns of threat- and deprivation-based childhood adversity and their impact on adolescent drinking, smoking, and depression.Child abuse & neglect · 2026Article
- A Mixed Methods Analysis of Risk and Support Factors for Prenatal Alcohol and Substance Use Among American Indian/Alaska Native Birthing People.Journal of racial and ethnic health disparities · 2026Article
- Associations Between Adverse Childhood Experiences and Physical Activity, Recreational Screen Time, and Sleep Among U.S. Children.Behavioral sciences (Basel, Switzerland) · 2026Article
- Teaching Youth & Families Self-Regulation Skills to Disrupt the Impact of Adverse Childhood Experiences: The THRIVE Study Protocol for a Randomized Controlled Trial.Research square · 2026Article
- Beyond Cumulative Risk: Gender-Specific Latent Class Patterns of Adverse Childhood Experiences and Systemic Inequities in Black Americans.Adversity and resilience science · 2026Article
- Productivity Losses From Substance Use Disorder in the U.S. in 2023.American journal of preventive medicine · 2026Article
- Violence and threat exposure is associated with frontostriatal alterations during risky decision-making in children with co-morbid ADHD and disruptive behavior disorders.Frontiers in psychiatry · 2026Article
- Psychiatric diagnosis and perceived health impact attributed to adverse childhood experiences: multidimensional impulsivity pathways in Saudi adults.Frontiers in psychiatry · 2026Article
- Patterns of Maternal and Paternal Adverse Childhood Experiences on Parenting Satisfaction and Parenting Stress.Journal of child and family studies · 2026Article
- Childhood exposure to interpersonal and animal-directed violence: adversity profiles and adult suicidality.Frontiers in psychiatry · 2026Article
- Article
- Exploring Pathways from Childhood Adversity to Substance Use in Young Adults.International journal of environmental research and public health · 2025Article
- Adverse childhood experiences and tobacco smoke exposure among U.S. school-aged children.Child protection and practice · 2025Article
- Latent Class Analysis of Household and Community Adversity Among Pre-Adolescent Youth in the United States.Child psychiatry and human development · 2025Article
- Association of maternal and paternal adverse childhood experiences with emotional and behavioral problems among preschool children.European child & adolescent psychiatry · 2025Article
55 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
introductionAdverse childhood experiences (ACEs) have been strongly linked with subsequent substance use. The aim of this study was to investigate how different patterns of ACEs influence substance use in young adulthood.
methodsUsing a community sample of young individuals (N=336; ages 18-25), we performed latent class analyses (LCA) to identify homogenous groups of young people with similar patterns of ACEs. Exposure to ACEs incorporates 13 childhood adversities including childhood maltreatment, household dysfunction, and community violence. Multiple linear and logistic regression models were used in an effort to examine the associations between ACEs classes and four young adult outcomes such as alcohol-related problems, current tobacco use, drug dependence symptoms, and psychological distress.
resultsLCA identified four heterogeneous classes of young people distinguished by different patterns of ACEs exposure: Low ACEs (56%), Household Dysfunction/Community Violence (14%), Emotional ACEs (14%), and High/Multiple ACEs (16%). Multiple regression analyses found that compared to those in the Low ACEs class, young adults in the High/Multiple ACEs class reported more alcohol-related problems, current tobacco use, and psychological symptoms, controlling for sociodemographic characteristics and common risk factors for substance use such as peer substance use.
conclusionsOur findings confirm that for many young people, ACEs occur as multiple rather than single experiences. The results of this research suggest that exposure to poly-victimization during childhood is particularly related to substance use during young adulthood.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.