ArticleMedical physics2018
Developing and characterizing MR/CT-visible materials used in QA phantoms for MRgRT systems.
Article in Medical physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 29 citations in OpenAlex.
- Silicone phantoms fabricated with multi-material extrusion 3D printing technology mimicking imaging properties of soft tissues in CT.Zeitschrift fur medizinische Physik · 2025Article
- End-to-end testing for stereotactic radiotherapy including the development of a Multi-Modality phantom.Zeitschrift fur medizinische Physik · 2024Article
- Regression fitting megavoltage depth dose curves to determine material relative electron density in radiotherapy.Physical and engineering sciences in medicine · 2023Article
- Investigation of silk as a phantom material for ultrasound and photoacoustic imaging.Photoacoustics · 2022Article
- Development of an anthropomorphic multimodality pelvic phantom for quantitative evaluation of a deep-learning-based synthetic computed tomography generation technique.Journal of applied clinical medical physics · 2022Article
- Mechanical and medical imaging properties of 3D-printed materials as tissue equivalent materials.Journal of applied clinical medical physics · 2022Article
- Standard MRI-based attenuation correction for PET/MRI phantoms: a novel concept using MRI-visible polymer.EJNMMI physics · 2021Article
- Medical physics challenges in clinical MR-guided radiotherapy.Radiation oncology (London, England) · 2020Review
- Physical imaging phantoms for simulation of tumor heterogeneity in PET, CT, and MRI: An overview of existing designs.Medical physics · 2020Review
- MRIgRT head and neck anthropomorphic QA phantom: Design, development, reproducibility, and feasibility study.Medical physics · 2020Article
- Evaluation of the accuracy of deformable image registration on MRI with a physical phantom.Journal of applied clinical medical physics · 2020Article
- Investigation of TLD and EBT3 performance under the presence of 1.5T, 0.35T, and 0T magnetic field strengths in MR/CT visible materials.Medical physics · 2019Article
- The role of dosimetry audit in achieving high quality radiotherapy.Physics and imaging in radiation oncology · 2018Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
purposeSynthetic tissue equivalent (STE) materials currently used to simulate tumor and surrounding tissues for IROC-Houston's anthropomorphic head and thorax QA phantoms cannot be visualized using magnetic resonance (MR) imaging. The purpose of this study was to characterize dual MR/CT-visible STE materials that can be used in an end-to-end QA phantom for MR-guided radiotherapy (MRgRT) modalities.
methodsOver 80 materials' MR, CT, and dosimetric STE properties were investigated for use in MRgRT QA phantoms. The materials tested included homogeneous and heterogeneous materials to simulate soft tissue/tumor and lung tissues. Materials were scanned on a Siemens' Magnetom Espree 1.5 T using four sequences, which showed the materials visual contrast between T1- and T2-weighted images. Each material's Hounsfield number and electron density data was collected using a GE's CT Lightspeed Simulator. Dosimetric properties were examined by constructing a 10 × 10 × 20 cm
resultsThe majority of the tested materials showed comparable CT attenuation properties to their respective organ site; however, most of the tested materials were not visible on either T1- or T2-weighted MR images. Silicone, hydrocarbon, synthetic gelatin, and liquid PVC plastic-based materials showed good MR image contrast. In-house lung equivalent materials made with either silicone- or hydrocarbon-based materials had HUs ranging from: -978 to -117 and -667 to -593, respectively. Synthetic gelatin and PVC plastic-based materials resembled soft tissue/tumor equivalent materials and had HUs of: -175 to -170 and -29 to 32, respectively. PDD curves of the selected MR/CT-visible materials were comparable to IROC-Houston's conventional phantom STE materials. The smallest field size showed the largest disagreements, where the average discrepancies between calculated and measured PDD curves were 1.8% and 5.9% for homogeneous and heterogeneous testing materials, respectively.
conclusionsGelatin, liquid plastic, and hydrocarbon-based materials were determined as alternative STE substitutes for MRgRT QA phantoms.
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