ArticleEnvironmental science and pollution research international2018
Cu(II)-catalyzed degradation of ampicillin: effect of pH and dissolved oxygen.
Article in Environmental science and pollution research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 28 citations in OpenAlex.
- The Domination of Penicillin G Degradation in Natural Surface Water: Effect of Calcium Ion and Biological Dissolved Organic Matter.Antibiotics (Basel, Switzerland) · 2025Article
- Genetically Engineered Yeast for Enhanced Biodegradation of Β-lactam Antibiotics.Applied biochemistry and biotechnology · 2025Article
- The Impact of Copper Ions on the Activity of Antibiotic Drugs.Molecules (Basel, Switzerland) · 2023Review
- Distinct effects of copper on the degradation ofEnvironmental science and ecotechnology · 2020Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Cu(II)-catalyzed hydrolysis of β-lactam antibiotics has been well-identified and recognized as the key mechanism of antibiotic degradation. However, the overlooked Cu(II) oxidation susceptibly also plays an important role comparably with hydrolysis. This study evaluated the roles of hydrolysis and oxidation in Cu(II)-catalyzed degraded ampicillin (AMP), as a typical β-lactam antibiotic, under relevant environmental conditions (pH 5.0, 7.0, and 9.0; oxygen 0.2 and 6.2 mg/L). Under AMP and Cu(II) molar ratio of 1:1, AMP degradation was the fastest at pH 9.0, followed by pH 5.0 and pH 7.0. The facilitation of oxygen on AMP degradation was notable at pH 5.0 and 7.0 rather than pH 9.0. AMP degradation rate increased from 21.8% in 0.2 mg/L O
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