ArticleAntonie van Leeuwenhoek2018
Research on the ability of propionic acid and vitamin B12 biosynthesis by Propionibacterium freudenreichii strain T82.
Article in Antonie van Leeuwenhoek, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 20 citations in OpenAlex.
- Production of Vitamin B12 by Propionibacterium freudenreichii subsp. shermanii ATCC 13673 on a Soybean Agroindustrial Waste-Based Medium: Bioprocess Optimization in STR Bioreactors.Applied biochemistry and biotechnology · 2026Article
- Enhanced vitamin BBMC biotechnology · 2024Article
- A hybrid RNA-protein biosensor for high-throughput screening of adenosylcobalamin biosynthesis.Synthetic and systems biotechnology · 2024Article
- Enhanced cobalamin biosynthesis inSynthetic and systems biotechnology · 2022Article
- The role of divalent iron cations in the growth, adhesive properties and extracellular adaptation mechanisms ofSaudi journal of biological sciences · 2022Article
- Metabolic Flux Analysis of Simultaneous Production of Vitamin BApplied biochemistry and biotechnology · 2021Article
- Metabolic profiling analysis of the vitamin BMicrobiologyOpen · 2021Article
- Environmental conditions modulate the protein content and immunomodulatory activity of extracellular vesicles produced by the probioticApplied and environmental microbiology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
The purpose of this study was to determine the potential for biosynthesis of propionic acid and vitamin B12 by Propionibacterium freudenreichii T82 in a medium containing various sources of carbon (glucose, fructose, and saccharose). These sugars are present in apple pomaces, which are the waste from the production of apple juice. Using statistical analysis design of experiments (DoE), the results allowed us to determine which sugars (carbon sources) exert the most beneficial influence on the biosynthesis of propionic acid and cobalamin. The highest production of propionic acid by the tested bacterial strain was obtained in a medium in which glucose accounted for at least 50% of the available carbon sources. Depending on the culture medium, the concentration of this metabolite ranged from 23 to 40 g/L. P. freudenreichii T82 produced the smallest amount of acid in medium in which the dominant nutrient source was saccharose. The results obtained indicated an inverse relationship between the amount of acid produced by the bacteria and vitamin B12 biosynthesis. Because of the high efficiency of propionic acid biosynthesis by P. freudenreichii T82, the prospect of using this strain to obtain propionate with the simultaneous disposal of waste materials (such as apple pomaces) which contain glucose and/or fructose is very promising.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.