Evidence map›Paper›PMID 29177947›Full record

ArticleArchives of microbiology2018

Effect of Lactobacillus rhamnosus on the response of Galleria mellonella against Staphylococcus aureus and Escherichia coli infections.

Adeline Lacerda Jorjão, Felipe Eduardo de Oliveira, Mariella Vieira Pereira Leão, Antonio Olavo Cardoso Jorge, Luciane Dias de Oliveira

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Antioxidant Potential ofMolecules (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Minor impact of probiotic bacteria and egg white onFrontiers in insect science · 2024
    Article
  10. Article
  11. The immunostimulatory role of anFrontiers in insect science · 2023
    Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Recent Advances in the Use ofJournal of fungi (Basel, Switzerland) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adeline Lacerda JorjãoDepartment of Biosciences and Oral Diagnosis, Laboratory of Microbiology and Immunology, Institute of Science and Technology, Paulista State University/UNESP, Av, Engenheiro Francisco José Longo, 777-Jardim São Dimas, São José dos Campos, SP, 12245-000, Brazil. adelinejorjao@gmail.com.
Felipe Eduardo de OliveiraDepartment of Biosciences and Oral Diagnosis, Laboratory of Microbiology and Immunology, Institute of Science and Technology, Paulista State University/UNESP, Av, Engenheiro Francisco José Longo, 777-Jardim São Dimas, São José dos Campos, SP, 12245-000, Brazil.
Mariella Vieira Pereira LeãoBioscience Basic Institute, University of Taubaté, Rua Expedicionário Ernesto Pereira, 3, Taubaté, São Paulo, Brazil.
Antonio Olavo Cardoso JorgeDepartment of Biosciences and Oral Diagnosis, Laboratory of Microbiology and Immunology, Institute of Science and Technology, Paulista State University/UNESP, Av, Engenheiro Francisco José Longo, 777-Jardim São Dimas, São José dos Campos, SP, 12245-000, Brazil.
Luciane Dias de OliveiraDepartment of Biosciences and Oral Diagnosis, Laboratory of Microbiology and Immunology, Institute of Science and Technology, Paulista State University/UNESP, Av, Engenheiro Francisco José Longo, 777-Jardim São Dimas, São José dos Campos, SP, 12245-000, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the prophylactic effects of the live or heat-killed probiotic strain Lactobacillus rhamnosus ATCC 7469 in Galleria mellonella, inoculated with Staphylococcus aureus or Escherichia coli. L. rhamnosus suspension was prepared and a part of it was autoclaved to obtain heat-killed lactobacilli. The larvae were inoculated of these suspensions and pathogenic. The survival of the larvae was observed during 7 days and after 24 h of inoculation haemocytes counted, melanization and nitric oxide production were analyzed. Larvae survival rate increased in the group inoculated with heat-killed L. rhamnosus, however, with no statistical difference. There was a significant increase in total haemocyte counts in all test groups. Haemolymph melanization and nitric oxide production were higher in the group inoculated with L. rhamnosus and infected with S. aureus. It was concluded that, in this model of infection, heat-killed L. rhamnosus ATCC 7469 promoted greater protection in Galleria mellonella infected with S. aureus or E. coli.

Indexed as

AnimalsEscherichia coliHemolymphHost-Pathogen InteractionsLacticaseibacillus rhamnosusLarvaMothsProbioticsStaphylococcus aureusCurve survivalGalleria mellonellaInfectionLactobacillus rhamnosusMelanization

Identifiers

PMID29177947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.