Evidence map›Paper›PMID 29177870›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2018

Dosimetric parameters predicting contralateral liver hypertrophy after unilobar radioembolization of hepatocellular carcinoma.

Xavier Palard, Julien Edeline, Yan Rolland, Samuel Le Sourd, Marc Pracht, Sophie Laffont, Laurence Lenoir, Karim Boudjema, Thomas Ugen, Vanessa Brun and 4 more

Open access · hybridAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 76 citations in OpenAlex.

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  19. The Role of Catheter-Directed CT-Angiography in Radioembolisation.Cardiovascular and interventional radiology · 2022
    Review
  20. Transarterial Radioembolization to Impact Liver Volumetry: When and How.Cardiovascular and interventional radiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Xavier PalardDepartment of Nuclear Medicine, Cancer Institute Eugène Marquis, Avenue de la Bataille Flandres-Dunkerque, CS 44229, 35042, Rennes cedex, France.
Julien EdelineUniversity of Rennes 1, 35033, Rennes, France.
Yan RollandDepartment of Medical Imaging, Cancer Institute Eugène Marquis, Avenue de la Bataille Flandres-Dunkerque, CS 44229, 35042, Rennes cedex, France.
Samuel Le SourdDepartment of Medical Oncology, Cancer Institute Eugène Marquis, Avenue de la Bataille Flandres-Dunkerque, CS 44229, 35042, Rennes cedex, France.
Marc PrachtDepartment of Medical Oncology, Cancer Institute Eugène Marquis, Avenue de la Bataille Flandres-Dunkerque, CS 44229, 35042, Rennes cedex, France.
Sophie LaffontDepartment of Nuclear Medicine, Cancer Institute Eugène Marquis, Avenue de la Bataille Flandres-Dunkerque, CS 44229, 35042, Rennes cedex, France.
Laurence LenoirDepartment of Nuclear Medicine, Cancer Institute Eugène Marquis, Avenue de la Bataille Flandres-Dunkerque, CS 44229, 35042, Rennes cedex, France.
Karim BoudjemaDepartment of Hepatobiliary Surgery, CHU Pontchaillou, 2 rue Henri le Guilloux, 35033, Rennes cedex, France.
Thomas UgenDepartment of Hepatology, CHU Pontchaillou, 35033, Rennes cedex, France.
Vanessa BrunDepartment of Medical Imaging, CHU Pontchaillou, 35033, Rennes cedex, France.
Habiba MesbahDepartment of Medical Information, Cancer Institute Eugène Marquis, Avenue de la Bataille Flandres-Dunkerque, CS 44229, 35042, Rennes cedex, France.
Laure-Anne HaumontDepartment of Medical Information, Cancer Institute Eugène Marquis, Avenue de la Bataille Flandres-Dunkerque, CS 44229, 35042, Rennes cedex, France.
Pascal LoyerINSERM, INRA, Univ Rennes 1, Univ Bretagne Loire, Nutrition Metabolisms and Cancer (NuMeCan), Rennes, France.
Etienne GarinDepartment of Nuclear Medicine, Cancer Institute Eugène Marquis, Avenue de la Bataille Flandres-Dunkerque, CS 44229, 35042, Rennes cedex, France. e.garin@rennes.unicancer.fr.ORCID 0000-0003-1416-2863
Centre Eugène Marquis · FRInserm · FRHôpital Pontchaillou · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed at identifying prior therapy dosimetric parameters using

methodsThe dosimetry data of 73 HCC patients were collected prior to the treatment with

resultsMean MHT was 35.4 ± 40.4%. When using continuous variables, the MHT was not correlated with any tested variable, i.e., injected activity, ILD, HILD or TD except with a percentage of future remnant liver (FRL) following the

conclusionThis study demonstrates for the first time that HILD is significantly associated with liver hypertrophy. There is also an impact of high tumor doses in large lesions in one subgroup of patients. Larger prospective studies evaluating the MAA dosimetric parameters have to be conducted to confirm these promising results.

Indexed as

AgedCarcinoma, HepatocellularEmbolization, TherapeuticFemaleHumansHypertrophyLiverLiver NeoplasmsMaleRadiometryRetrospective StudiesTechnetium Tc 99m Aggregated AlbuminYttrium RadioisotopesTechnetium Tc 99m Aggregated AlbuminYttrium-90Yttrium Radioisotopes90Y–loaded glass microspheres99mTc-labeled albuminHepatocellular carcinomaLiver hypertrophyPredictive dosimetryRadioembolization

Identifiers

PMID29177870
PMCPMC5787216
OpenAlexW2770323513

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.