Evidence map›Paper›PMID 29177811›Full record

ReviewIndian journal of pediatrics2018

Genetic and Syndromic Causes of Obesity and its Management.

Ildiko H Koves, Christian Roth

Abstract readReview
PubMed Publisher
In one paragraph

Review in Indian journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Management of Childhood Obesity.International journal of molecular sciences · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. A comprehensive review of genetic causes of obesity.World journal of pediatrics : WJP · 2024
    Review
  6. Article
  7. Review
  8. Novel Mutations in theCase reports in ophthalmological medicine · 2022
    Article
  9. Review
  10. Genetic Determinants of Childhood Obesity.Molecular diagnosis & therapy · 2020
    Review
  11. Review
  12. Article
  13. Cardiometabolic risk in obese children.Annals of the New York Academy of Sciences · 2018
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ildiko H KovesDivision of Endocrinology and Diabetes, Department of Pediatrics, Seattle Children's Hospital, University of Washington, 4800 Sand Point Way NE, Seattle, WA, 98105, USA. Ildiko.koves@seattlechildrens.org.
Christian RothDivision of Endocrinology and Diabetes, Department of Pediatrics, Seattle Children's Hospital, University of Washington, 4800 Sand Point Way NE, Seattle, WA, 98105, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this article is to provide an in depth review of the rare genetic and syndromic forms of childhood obesity. The authors demonstrate the complexity and inter-relationships of the leptin-melanocortin signaling pathway and its central nervous system and systemic effects. Authors highlight the clinical distinctive features of genetic/syndromic causes for childhood obesity, in particular, relative shorter height to their genetic potential, developmental challenges and in some instances, ophthalmological and retina changes. They outline specific genetic testing and treatment options available for these conditions.

Indexed as

Genetic TestingChildHumansLeptinMelanocortinsPediatric ObesitySignal TransductionSyndromeLeptinMelanocortinsClinical assessmentLeptin-melanocortin signaling pathwayMonogenic obesitySyndromic obesity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.