Evidence map›Paper›PMID 29177804›Full record

ArticleSkeletal radiology2018

MRI of the sacroiliac joints in spondyloarthritis: the added value of intra-articular signal changes for a 'positive MRI'.

Frederiek Laloo, N Herregods, J L Jaremko, K Verstraete, L Jans

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Article in Skeletal radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. New Bone Formation in Axial Spondyloarthritis: A Review.RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin · 2024
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Frederiek LalooDepartment of Radiology and Medical Imaging, Ghent University Hospital, De Pintelaan 185, B-9000, Ghent, Belgium. Frederiek.Laloo@UGent.be.
N HerregodsDepartment of Radiology and Medical Imaging, Ghent University Hospital, De Pintelaan 185, B-9000, Ghent, Belgium.
J L JaremkoDepartment of Radiology & Diagnostic Imaging, University of Alberta Hospital, 8440-112 Street, Edmonton, AB, T6G 2B7, Canada.
K VerstraeteDepartment of Radiology and Medical Imaging, Ghent University Hospital, De Pintelaan 185, B-9000, Ghent, Belgium.
L JansDepartment of Radiology and Medical Imaging, Ghent University Hospital, De Pintelaan 185, B-9000, Ghent, Belgium.
Ghent University Hospital · BEUniversity of Alberta Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine if intra-articular signal changes at the sacroiliac joint space on MRI have added diagnostic value for spondyloarthritis, when compared to bone marrow edema (BME). MATERIALS AND

methodsA retrospective study was performed on the MRIs of sacroiliac joints of 363 patients, aged 16-45 years, clinically suspected of sacroiliitis. BME of the sacroiliac joints was correlated to intra-articular sacroiliac joint MR signal changes: high T1 signal, fluid signal, ankylosis and vacuum phenomenon (VP). These MRI findings were correlated with final clinical diagnosis. Sensitivity (SN), specificity (SP), likelihood ratios (LR), predictive values and post-test probabilities were calculated.

resultsBME had SN of 68.9%, SP of 74.0% and LR+ of 2.6 for diagnosis of spondyloarthritis. BME in absence of intra-articular signal changes had a lower SN and LR+ for spondyloarthritis (SN = 20.5%, LR+ 1.4). Concomitant BME and high T1 signal (SP = 97.2%, LR + = 10.5), BME and fluid signal (SP = 98.6%, LR + = 10.3) or BME and ankylosis (SP = 100%) had higher SP and LR+ for spondyloarthritis. Concomitant BME and VP had low LR+ for spondyloarthritis (SP = 91%, LR + =0.9). When BME was absent, intra-articular signal changes were less prevalent, but remained highly specific for spondyloarthritis.

conclusionOur results suggest that both periarticular and intra-articular MR signal of the sacroiliac joint should be examined to determine whether an MRI is 'positive' or 'not positive' for sacroiliitis associated with spondyloarthritis.

Indexed as

AdolescentAdultEdemaFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPredictive Value of TestsRetrospective StudiesSacroiliac JointSacroiliitisSensitivity and SpecificitySpondylarthritisAnkylosisMRISacroiliac jointSacroiliitisSpondyloarthritis

Identifiers

PMID29177804
OpenAlexW2768148120

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.