ArticleNeuroradiology2018
Carotid near-occlusion frequently has high peak systolic velocity on Doppler ultrasound.
Article in Neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Carotid near-occlusion diagnostics and its consequences: A systematic review.European stroke journal · 2026Pooled it
- Short-term risk of recurrent stroke in symptomatic carotid near-occlusion: pooled analysis of three cohort studies.European stroke journal · 2026Article
- Duplex ultrasound in severe carotid stenosis: diagnostic performance for differentiating near-occlusion subtypes from conventional high-grade stenosis.Neuroradiology · 2026Article
- Sex differences in patients with symptomatic carotid stenosis included in three observational cohorts.European stroke journal · 2026Observational
- Carotid near-occlusion diagnostics and its consequences: A systematic review.European stroke journal · 2025Review
- Rule-out and rule-in of carotid near-occlusion using color duplex ultrasound.Neuroradiology · 2025Article
- The pitfalls and challenges in the diagnosis and treatment of patients with carotid near-occlusion: a narrative review.Quantitative imaging in medicine and surgery · 2024Review
- Phase-contrast magnetic resonance imaging of intracranial and extracranial blood flow in carotid near-occlusion.Neuroradiology · 2024Article
- Diagnostic separation of conventional ⩾50% carotid stenosis and near-occlusion with phase-contrast MRI.European stroke journal · 2024Article
- Defining carotid near-occlusion with full collapse: a pooled analysis.Neuroradiology · 2022Article
- Ultrasonographic and hemodynamic characteristics of patients with symptomatic carotid near-occlusion: results from a multicenter registry study.Neuroradiology · 2021Article
- Diagnosing Carotid Near-Occlusion with Phase-Contrast MRI.AJNR. American journal of neuroradiology · 2021Article
- Near-occlusion is difficult to diagnose with common carotid ultrasound methods.Neuroradiology · 2021Article
- High-Frame Rate Vector Flow Imaging Technique: Initial Application in Evaluating the Hemodynamic Changes of Carotid Stenosis Caused by Atherosclerosis.Frontiers in cardiovascular medicine · 2021Article
- Symptomatic carotid near-occlusion causes a high risk of recurrent ipsilateral ischemic stroke.Journal of neurology · 2020Article
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCarotid near-occlusion is a tight atherosclerotic stenosis of the internal carotid artery (ICA) resulting in decrease in diameter of the vessel lumen distal to the stenosis. Near-occlusions can be classified as with or without full collapse, and may have high peak systolic velocity (PSV) across the stenosis, mimicking conventional > 50% carotid artery stenosis. We aimed to determine how frequently near-occlusions have high PSV in the stenosis and determine how accurately carotid Doppler ultrasound can distinguish high-velocity near-occlusion from conventional stenosis.
methodsIncluded patients had near-occlusion or conventional stenosis with carotid ultrasound and CT angiogram (CTA) performed within 30 days of each other. CTA examinations were analyzed by two blinded expert readers. Velocities in the internal and common carotid arteries were recorded. Mean velocity, pulsatility index, and ratios were calculated, giving 12 Doppler parameters for analysis.
resultsOf 136 patients, 82 had conventional stenosis and 54 had near-occlusion on CTA. Of near-occlusions, 40 (74%) had high PSV (≥ 125 cm/s) across the stenosis. Ten Doppler parameters significantly differed between conventional stenosis and high-velocity near-occlusion groups. However, no parameter was highly sensitive and specific to separate the groups.
conclusionNear-occlusions frequently have high PSV across the stenosis, particularly those without full collapse. Carotid Doppler ultrasound does not seem able to distinguish conventional stenosis from high-velocity near-occlusion. These findings question the use of ultrasound alone for preoperative imaging evaluation.
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