ArticleBioprocess and biosystems engineering2018
Recombinant biosynthesis of bacterial cellulose in genetically modified Escherichia coli.
Article in Bioprocess and biosystems engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 76 citations in OpenAlex.
- Bioengineering microbial cellulose synthesis pathways as biofactory for industrial-scale cellulose production: a review on current advances.World journal of microbiology & biotechnology · 2026Review
- Biocircular economy-driven bacterial cellulose with large pore size: statistical optimization using Glutamicibacter soli bread waste hydrolysate.Bioresources and bioprocessing · 2026Article
- Kombucha-Derived Cellulose Non-wovens: Growth Optimization, Mechanics, and Recycling.bioRxiv : the preprint server for biology · 2026Article
- Microbial Valorization of Agricultural and Agro-Industrial Waste into Bacterial Cellulose: Innovations for Circular Bioeconomy Integration.Microorganisms · 2025Review
- Cellulose-Based Hybrid Hydrogels for Tissue Engineering Applications: A Sustainable Approach.Gels (Basel, Switzerland) · 2025Review
- Effect of Quorum Sensing Molecules on the Quality of Bacterial Nanocellulose Materials.ACS omega · 2024Article
- From Nature to Lab: Sustainable Bacterial Cellulose Production and Modification with Synthetic Biology.Polymers · 2023Review
- Bacterial crystalline cellulose secretion via a supramolecular BcsHD scaffold.Science advances · 2022Article
- Harnessing bioengineered microbes as a versatile platform for space nutrition.Nature communications · 2022Review
- Research progress of the biosynthetic strains and pathways of bacterial cellulose.Journal of industrial microbiology & biotechnology · 2022Review
- Bacterial Cellulose: Production, Characterization, and Application as Antimicrobial Agent.International journal of molecular sciences · 2021Review
- Production of bacterial cellulose from glycerol: the current state and perspectives.Bioresources and bioprocessing · 2021Review
- Systematic Understanding of Recent Developments in Bacterial Cellulose Biosynthesis at Genetic, Bioprocess and Product Levels.International journal of molecular sciences · 2021Review
- Enhanced Production of Bacterial Cellulose inJournal of microbiology and biotechnology · 2020Article
- Industrial-Scale Production and Applications of Bacterial Cellulose.Frontiers in bioengineering and biotechnology · 2020Review
- The Suitability of Orthogonal Hosts to Study Plant Cell Wall Biosynthesis.Plants (Basel, Switzerland) · 2019Review
- Bacterial cellulose: a versatile biopolymer for wound dressing applications.Microbial biotechnology · 2019Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacterial cellulose (BC) exhibits unique properties such as high purity compared to plant-based cellulose; however, commercial production of BC has remained a challenge, primarily due to the strain properties of cellulose-producing bacteria. Herein, we developed a functional and stable BC production system in genetically modified (GM) Escherichia coli by recombinant expression of both the BC synthase operon (bcsABCD) and the upstream operon (cmcax, ccp Ax). BC production was achieved in GM HMS174 (DE3) and in GM C41 (DE3) by optimization of the culture temperature (22 °C, 30 °C, and 37 °C) and IPTG concentration. BC biosynthesis was detected much earlier in GM C41 (DE3) cultures (3 h after IPTG induction) than those of Gluconacetobacter hansenii. GM HMS174 (DE3) produced dense fibres having a length of approximately 1000-3000 μm and a diameter of 10-20 μm, which were remarkably larger than the fibres of BC typically produced by G. hansenii.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.