ArticleEuropean journal of clinical pharmacology2018
Longitudinal patterns of potentially inappropriate prescribing in early old-aged people.
Article in European journal of clinical pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Identification of behaviour change techniques in deprescribing interventions: a systematic review and meta-analysis.British journal of clinical pharmacology · 2018Pooled it
- Applicability of STOPP/START prescribing criteria in integrated Swedish administrative health registries and a Swedish population-based cohort.European geriatric medicine · 2024Observational
- Use of potentially inappropriate medication for elderly patients in tertiary care hospital of Riyadh, Saudi Arabia.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024Article
- Potentially Inappropriate Medications in Older Adults-Prevalence, Trends and Associated Factors: A Cross-Sectional Study in Saudi Arabia.Healthcare (Basel, Switzerland) · 2023Article
- Sedatives and analgesics are major contributors to potentially inappropriate duplicate prescriptions in geriatric psychiatry.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2023Article
- Cohort profile update: The Cork and Kerry Diabetes and Heart Disease Study.HRB open research · 2023Article
- Healthcare costs of adverse drug reactions and potentially inappropriate prescribing in older adults: a population-based study.BMJ open · 2022Article
- Autonomous Tool for Monitoring Multi-Morbidity Health Conditions in UAE and India.Frontiers in artificial intelligence · 2022Review
- An Update on Medication Use in Older Adults: a Narrative Review.Current epidemiology reports · 2021Review
- Barriers to effective prescribing in older adults: applying the theoretical domains framework in the ambulatory setting - a scoping review.BMC geriatrics · 2020Article
- One-year persistence of potentially inappropriate medication use in older adults: A population-based study.British journal of clinical pharmacology · 2020Article
- 'Modified STOPP-START criteria for Sri Lanka'; translating to a resource limited healthcare setting by Delphi consensus.BMC geriatrics · 2019Article
- Prescribing issues in older adults living with HIV: thinking beyond drug-drug interactions with antiretroviral drugs.Therapeutic advances in drug safety · 2019Article
- The associations of geriatric syndromes and other patient characteristics with the current and future use of potentially inappropriate medications in a large cohort study.European journal of clinical pharmacology · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposeIt is contentious whether potentially inappropriate prescribing (PIP) is predominantly a phenomenon of late life or whether it has its origins in early old age. This study examined the pattern of PIP in an early old-aged population over 5 years.
methodsSecondary data analysis of a population-based primary care cohort, of patients aged 60-74 years. Medication data were extracted from electronic patient records in addition to information on comorbidities and demographics. Explicit START criteria (PPOs) and STOPP criteria (PIMs) were used to identify PIP. Generalised estimating equations were used to describe trends in PIP over time and adjusted for age, gender and number of medicines.
resultsA total of 978 participants (47.8%) aged 60-74 years were included from the cohort. At baseline, PPOs were detected in 31.2% of patients and PIMs were identified in 35.6% at baseline. Prevalence of PPOs and PIMs increased significantly over time (OR 1.08, 95% CI 1.07; 1.09 and OR 1.04, 95% CI 1.0; 1.06, respectively). A higher number of medicines and new diagnoses were associated with the increasing trend in both PPO and PIM prevalence observed over time, independent of PPOs and PIMs triggered by drug combinations.
conclusionsPotentially inappropriate prescribing is highly prevalent among early old-aged people in primary care and increases as they progress to more advanced old age, suggesting that routine application of STOPP/START criteria in this population would significantly improve medication appropriateness.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.