Evidence map›Paper›PMID 29177130›Full record

ArticleCurrent sleep medicine reports2017

Sleep Disordered Breathing and Spinal Cord Injury: Challenges and Opportunities.

Abdulghani Sankari, Jennifer L Martin, M Safwan Badr

Abstract read
In one paragraph

Article in Current sleep medicine reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Observational
  3. An update on sleep disordered breathing in spinal cord injury.Current opinion in pulmonary medicine · 2025
    Review
  4. Insomnia severity predicts depression, anxiety, and posttraumatic stress disorder in veterans with spinal cord injury or disease: a cross-sectional observational study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Observational
  5. Observational
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Abdulghani SankariJohn D. Dingell VA Medical Center, Detroit, MI, USA.
Jennifer L MartinVA Greater Los Angeles Healthcare System, North Hills, CA, USA.
M Safwan BadrJohn D. Dingell VA Medical Center, Detroit, MI, USA.
John D. Dingell VA Medical Center · USUniversity of California, Los Angeles · USWayne State University · US

Funding

Sleep-Disordered Breathing in patients with C-SCI: Mechanisms and TherapyR01HL130552 · NHLBI · WAYNE STATE UNIVERSITY · PI BADR, M.SAFWAN · 2016 to 2020
$1.5M
Sleep disordered breathing and cardiovascular outcome: New approach and secondary analysis.R21HL140447 · NHLBI · WAYNE STATE UNIVERSITY · PI SANKARI, ABDULGHANI · 2017 to 2018
$231k
Sleep and Breathing in Patients With Spinal Cord InjuryI01CX001040 · VA · JOHN D DINGELL VA MEDICAL CENTER · PI BADR, M.SAFWAN · 2014 to 2017
–
Does Treatment of Sleep-Disordered Breathing Improve Functional Outcomes in SCI?I01RX002116 · VA · JOHN D DINGELL VA MEDICAL CENTER · PI BADR, M.SAFWAN · 2017 to 2020
–
Pathogenesis of Sleep Disordered Breathing in Spinal Cord Injury PatientsIK2CX000547 · VA · JOHN D DINGELL VA MEDICAL CENTER · PI SANKARI, ABDULGHANI · 2013 to 2019
–
CSRD VA I01 CX001040CSRD VA IK2 CX000547NHLBI NIH HHS R01 HL130552RRD VA I01 RX002116
6 · The paper itself

Abstract

purpose of reviewThis paper focuses on the sleep disorders in patients with spinal cord injury (SCI/D), particularly mechanism of sleep disordered breathing (SDB) and challenges in diagnosis and management. Based on a review of recent literatures and studies the paper summarizes some main challenges with respect to management of SDB in patients with SCI; and what are the responsible mechanisms of disease? What are the barriers in diagnosing and treating SDB using standard treatment such as positive airway pressure (CPAP)?. RECENT

findingsPrevious studies have shown that most SCI/D patients have SDB with heterogeneity in prevalence mainly related to using different definition or methods of diagnosing SDB, while recent studies using new definition of SDB based on recommended criteria from the American Academy of Sleep Medicine (AASM) and also include the data on effect of SCI/D level on prevalence and describe different type of SDB. Furthermore, recent data describes simplified method of diagnosing SDB by using a combination of home sleep apnea testing and transcutaneous CO2 monitoring. Finally, emerging data has been pointing at strong relationship between SDB and cardiovascular disease including nocturnal hypertension in patients with SCI/D. SUMMARY: The findings indicate that early testing for SDB and associated cardiovascular disease in patients with SCI is recommended and could be beneficial in reduced the high morbidity and mortality in this group of patients with disability. In addition, studies on treatment of other sleep disorders in SCI/D are not available to inform clinical decision making. Understanding the pathophysiology of sleep disorders in SCI/D is critical for the development of new effective therapies. This review provides evidence for best practices; highlights new discoveries for the diagnosis and management of sleep disorders in SCI/D, and discuss challenges and future directions.

Indexed as

periodic legs movementssleep-disordered breathingsleep disturbancesspinal cord injurytetraplegia

Identifiers

PMID29177130
PMCPMC5697765
OpenAlexW2767031145

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.