ArticlePloS one2017
Prevalence of fimA genotypes of Porphyromonas gingivalis in adolescent orthodontic patients.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The efficacy of mouthwashes on oral microorganisms and gingivitis in patients undergoing orthodontic treatment: a systematic review and meta-analysis.BMC oral health · 2023Pooled it
- Oral health in adolescents: periodontal inflammatory biomarkers during orthodontic clear aligner therapy.Clinical oral investigations · 2025Article
- Dynamics of the oral microbiome during orthodontic treatment and antimicrobial advances for orthodontic appliances.iScience · 2024Review
- The Influence of Orthodontic Treatment on Periodontal Health between Challenge and Synergy: A Narrative Review.Dentistry journal · 2024Review
- White spot lesions in orthodontics: consensus statements for prevention and management.The Angle orthodontist · 2023Article
- Detection and quantification of pathogens in saliva of adolescents with cerebral palsy: a cross-sectional study.Frontiers in dental medicine · 2023Article
- Anti-Adherence and Antimicrobial Activities of Silver Nanoparticles against SerotypesMedicina (Kaunas, Lithuania) · 2022Article
- The Oral Microbiota Changes in Orthodontic Patients and Effects on Oral Health: An Overview.Journal of clinical medicine · 2021Review
- Taxonomic Analysis of Oral Microbiome during Orthodontic Treatment.International journal of dentistry · 2021Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe placement of fixed orthodontic appliances may alter the composition of oral microbiota and has the potential risk of periodontal complication. Porphyromonas gingivalis fimbriae play a critical role in colonization of P. gingivalis in subgingival regions. In this study, we investigated the association between the prevalence of P. gingivalis-specific fimA genotypes and periodontal health status in adolescent orthodontic patients, to identify the pathogencity of P. gingivalis during orthodontic therapy.
methodsSixty-one adolescent orthodontic patients were enrolled in the case group, while the control group consisted of 56 periodontally healthy adolescents. At baseline (T0), clinical parameter (gingival index) was tested, and subgingival plaque samples were obtained from the lower incisors. The incidences of P. gingivalis and fimA genotypes were detected by polymerase chain reaction. All parameters were reassessed after 1 month (T1), 2 months (T2), 3 months (T3), and 6 months (T4) in the case group and then compared with those of the controls.
resultsBoth microbiological and clinical parameters from orthodontic patients started to increase after placement of fixed appliances. Maximum values were reached at 3 months after placement and followed by their decreases at six months. However, the microbiological and clinical parameters in the case group were significantly higher than those of the control group. The GI of fimA II, IV-positive samples was significantly higher than that of negative samples.
conclusionP. gingivalis carrying fimA II or IV was closely related to orthodontic gingivitis. In addition, proper oral hygiene control could lead to little increase in dental plaque accumulation, and exert a beneficial effect to periodontal tissues.
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