Evidence map›Paper›PMID 29176849›Full record

ArticlePloS one2017

Association between non-barrier modern contraceptive use and condomless sex among HIV-positive female sex workers in Mombasa, Kenya: A prospective cohort analysis.

Diya Surie, Krista Yuhas, Kate Wilson, Linnet N Masese, Juma Shafi, John Kinuthia, Walter Jaoko, R Scott McClelland

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Diya SurieDepartment of Medicine, University of Washington, Seattle, United States of America.
Krista YuhasDepartment of Global Health, University of Washington, Seattle, United States of America.
Kate WilsonDepartment of Global Health, University of Washington, Seattle, United States of America.
Linnet N MaseseDepartment of Medicine, University of Washington, Seattle, United States of America.
Juma ShafiInstitute of Tropical and Infectious Diseases, University of Nairobi, Nairobi, Kenya.
John KinuthiaDepartments of Research and Programs, Reproductive Health, Kenyatta National Hospital, Nairobi, Kenya.
Walter JaokoKenya AIDS Vaccine Initiative Institute, University of Nairobi, Nairobi, Kenya.
R Scott McClellandDepartment of Medicine, University of Washington, Seattle, United States of America.ORCID http://orcid.org/0000-0003-2574-4201
University of Washington · USUniversity of Nairobi · KEKenyatta National Hospital · KE

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI EDWIN ROBERTO ORELLANA · 1988 to 2026
$104.9M
Women's Life Events & HIV Transmission Potential: A Multidisciplinary StudyR01HD072617 · NICHD · UNIVERSITY OF WASHINGTON · PI MCCLELLAND, RAYMOND SCOTT · 2012 to 2016
$2.1M
NIAID NIH HHS P30 AI027757NICHD NIH HHS R01 HD072617
6 · The paper itself

Abstract

backgroundAs access to antiretroviral therapy in sub-Saharan Africa continues to expand, more women with HIV can expect to survive through their reproductive years. Modern contraceptives can help women choose the timing and spacing of childbearing. However, concerns remain that women with HIV who use non-barrier forms of modern contraception may engage in more condomless sex because of their decreased risk of unintended pregnancy. We examined whether non-barrier modern contraceptive use by HIV-positive female sex workers was associated with increased frequency of recent condomless sex, measured by detection of prostate-specific antigen (PSA) in vaginal secretions.

methodsWomen who were HIV-positive and reported transactional sex were included in this analysis. Pregnant and post-menopausal follow-up time was excluded, as were visits at which women reported trying to get pregnant. At enrollment and quarterly follow-up visits, a pelvic speculum examination with collection of vaginal secretions was conducted for detection of PSA. In addition, women completed a structured face-to-face interview about their current contraceptive methods and sexual risk behavior at enrollment and monthly follow-up visits. Log-binomial generalized estimating equations regression was used to test for associations between non-barrier modern contraceptive use and detection of PSA in vaginal secretions and self-reported condomless sex. Data from October 2012 through September 2014 were included in this analysis.

resultsOverall, 314 women contributed 1,583 quarterly examination visits. There was minimal difference in PSA detection at contraceptive-exposed versus contraceptive-unexposed visits (adjusted relative risk [aRR] 1.28, 95% confidence interval [95% CI] 0.93-1.76). There was a higher rate of self-reported condomless sex at visits where women reported using modern contraceptives, but this difference was not statistically significant after adjustment for potential confounding factors (aRR 1.59, 95% CI 0.98-2.58).

conclusionNon-barrier methods of modern contraception were not associated with increased risk of objective evidence of condomless sex.

Indexed as

Sexual BehaviorAdultCondomsContraception BehaviorFemaleHIV SeropositivityHumansKenyaProspective StudiesProstate-Specific AntigenSelf ReportSex WorkersVaginaProstate-Specific Antigen

Identifiers

PMID29176849
PMCPMC5703462
OpenAlexW2770187445

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.