Evidence map›Paper›PMID 29176738›Full record

ArticleScientific reports2017

Induction of Immune Surveillance of the Dysmorphogenic Lens.

Caitlin M Logan, Caitlin J Bowen, A Sue Menko

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. FoxO1 promotes high glucose-induced inflammation and cataract formation via JAK1/STAT1.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
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  5. Review
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  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Uveitis-mediated immune cell invasion through the extracellular matrix of the lens capsule.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Article
  18. Article
  19. Immune responses to injury and their links to eye disease.Translational research : the journal of laboratory and clinical medicine · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Caitlin M LoganThomas Jefferson University, Department of Pathology, Anatomy and Cell Biology, Philadelphia, Pennsylvania, 19107, United States.
Caitlin J BowenThomas Jefferson University, Department of Pathology, Anatomy and Cell Biology, Philadelphia, Pennsylvania, 19107, United States.
A Sue MenkoThomas Jefferson University, Department of Pathology, Anatomy and Cell Biology, Philadelphia, Pennsylvania, 19107, United States. sue.menko@jefferson.edu.
Thomas Jefferson University · US

Funding

Paradigms of Wound Healing and Fibrosis in the EyeR01EY021784 · NEI · THOMAS JEFFERSON UNIVERSITY · PI A. Sue Menko, Mary Ann Stepp · 2011 to 2026
$7.3M
Tyrosine Phosphorylation in Lens Cell DifferentiationR01EY014258 · NEI · THOMAS JEFFERSON UNIVERSITY · PI MENKO, A. SUE · 2003 to 2015
$3.9M
NEI NIH HHS R01 EY014258NEI NIH HHS R01 EY021784
6 · The paper itself

Abstract

The lens has been considered to be an immune privileged site not susceptible to the immune processes normally associated with tissue injury and wound repair. However, as greater insight into the immune surveillance process is gained, we have reevaluated the concept of immune privilege. Our studies using an N-cadherin lens-specific conditional knockout mouse, N-cad

Indexed as

Immunologic SurveillanceAnimalsAnophthalmosCadherinsEyeLymphatic VesselsMiceMicrophthalmosCadherins

Identifiers

PMID29176738
PMCPMC5701161
OpenAlexW2769414836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.