Evidence map›Paper›PMID 29176619›Full record

ArticleNature communications2017

STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells.

Paula Nunes-Hasler, Sophia Maschalidi, Carla Lippens, Cyril Castelbou, Samuel Bouvet, Daniele Guido, Flavien Bermont, Esen Y Bassoy, Nicolas Page, Doron Merkler and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. CRAC channels as targets for immunotherapy.Current opinion in immunology · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. CaBiophysics reports · 2024
    Article
  9. Article
  10. Review
  11. A Putative Role for TRPC6 in Immune-Mediated Kidney Injury.International journal of molecular sciences · 2023
    Review
  12. STIM1 in tumor cell death: angel or devil?Cell death discovery · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Localisation of Intracellular Signals and Responses during Phagocytosis.International journal of molecular sciences · 2023
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 3 countries.

Paula Nunes-HaslerDepartment of Cell Physiology and Metabolism, University of Geneva, Geneva, 1211, Switzerland. Paula.Nunes@unige.ch.ORCID http://orcid.org/0000-0002-4598-685X
Sophia MaschalidiLaboratory of Normal and Pathological Homeostasis of the Immune System, INSERM UMR1163, Paris, 75015, France.
Carla LippensDepartment of Pathology and Immunology, University of Geneva, Geneva, 1211, Switzerland.
Cyril CastelbouDepartment of Cell Physiology and Metabolism, University of Geneva, Geneva, 1211, Switzerland.
Samuel BouvetDepartment of Cell Physiology and Metabolism, University of Geneva, Geneva, 1211, Switzerland.
Daniele GuidoDepartment of Cell Physiology and Metabolism, University of Geneva, Geneva, 1211, Switzerland.
Flavien BermontDepartment of Cell Physiology and Metabolism, University of Geneva, Geneva, 1211, Switzerland.
Esen Y BassoyDepartment of Cell Physiology and Metabolism, University of Geneva, Geneva, 1211, Switzerland.ORCID http://orcid.org/0000-0001-8870-7040
Nicolas PageDepartment of Pathology and Immunology, University of Geneva, Geneva, 1211, Switzerland.
Doron MerklerDepartment of Pathology and Immunology, University of Geneva, Geneva, 1211, Switzerland.
Stéphanie HuguesDepartment of Pathology and Immunology, University of Geneva, Geneva, 1211, Switzerland.
Denis MartinvaletDepartment of Cell Physiology and Metabolism, University of Geneva, Geneva, 1211, Switzerland.
Bénédicte ManouryUniversité Paris Descartes, Sorbonne Paris Cité, Faculté de médecine Paris Descartes, Paris, 75015, France.
Nicolas DemaurexDepartment of Cell Physiology and Metabolism, University of Geneva, Geneva, 1211, Switzerland.ORCID http://orcid.org/0000-0002-9933-6772
University of Geneva · CHDélégation Paris 5 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antigen cross-presentation by dendritic cells (DC) stimulates cytotoxic T cell activation to promote immunity to intracellular pathogens, viruses and cancer. Phagocytosed antigens generate potent T cell responses, but the signalling and trafficking pathways regulating their cross-presentation are unclear. Here, we show that ablation of the store-operated-Ca

Indexed as

AnimalsAntigen PresentationCalciumCell MovementCystinyl AminopeptidaseDendritic CellsEndoplasmic ReticulumHydrogen-Ion ConcentrationMice, KnockoutPhagocytosisPhagosomesReactive Oxygen SpeciesStromal Interaction Molecule 1CalciumCystinyl Aminopeptidaseleucyl-cystinyl aminopeptidaseReactive Oxygen SpeciesStim1 protein, mouseStromal Interaction Molecule 1

Identifiers

PMID29176619
PMCPMC5701258
OpenAlexW2770872748

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.