Evidence map›Paper›PMID 29176536›Full record

ArticleRetinal cases & brief reports2020

PARACENTRAL ACUTE MIDDLE MACULOPATHY ASSOCIATED WITH BILATERAL OPTIC DISK SWELLING AND MENINGITIS.

Zhenyang Zhao, Parker Faith, Kaivon Pakzad-Vaezi, Zhongdi Chu, Ruikang K Wang, Raghu C Mudumbai, Kasra A Rezaei

Open access · greenAbstract readCase Reports
In one paragraph

Article in Retinal cases & brief reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Paracentral acute middle maculopathy-review of the literature.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
    Review
  3. 14th EUNOS Congress: PORTO, PORTUGAL, 16-19 JUNE 2019.Neuro-ophthalmology (Aeolus Press) · 2019
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zhenyang ZhaoDepartment of Ophthalmology, The University of Texas Medical Branch, Galveston, Texas.
Parker FaithDepartment of Ophthalmology, University of Washington Medicine, Seattle, Washington; and.
Kaivon Pakzad-VaeziDepartment of Ophthalmology, University of Washington Medicine, Seattle, Washington; and.
Zhongdi ChuDepartment of Ophthalmology, University of Washington Medicine, Seattle, Washington; and.
Ruikang K WangDepartment of Ophthalmology, University of Washington Medicine, Seattle, Washington; and.
Raghu C MudumbaiDepartment of Ophthalmology, University of Washington Medicine, Seattle, Washington; and.
Kasra A RezaeiDepartment of Ophthalmology, University of Washington Medicine, Seattle, Washington; and.
University of Washington · USThe University of Texas Medical Branch at Galveston · US

Funding

NON-INVASIVE REAL-TIME LABEL-FREE 3D IMAGING OF RETINAL MICROCIRCULATIONR01EY024158 · NEI · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2014 to 2017
$1.7M
NEI NIH HHS R01 EY024158
6 · The paper itself

Abstract

background/purposeTo present a novel case of paracentral acute middle maculopathy associated with bilateral optic disk swelling.

methodsRetrospective case report.

resultsA 67-year-old woman presented with sudden onset of central vision loss and subsequent bilateral optic disk edema, retinal vessel attenuation, and anterior uveitis. Cerebrospinal fluid analysis showed signs of inflammation. Spectral domain optical coherence tomography demonstrated the pathognomonic hyperreflectivity of the middle retinal layers consistent with paracentral acute middle maculopathy. Swept-source optical coherence tomography angiography with custom vessel analysis demonstrated a 18.3% decrease in the deep retinal vascular density and 2.4 times increase in absent flow area in the affected eye compared with the fellow eye.

conclusionThis case demonstrates a novel association between paracentral acute middle maculopathy and bilateral optic disk swelling secondary to central nervous system inflammation and possible infection. Although spectral domain optical coherence tomography is valuable in detecting paracentral acute middle maculopathy, optical coherence tomography angiography with vessel analysis can provide additional insight into the disease mechanism.

Indexed as

Acute DiseaseAgedFemaleFluorescein AngiographyFundus OculiHumansMacula LuteaMagnetic Resonance ImagingMeningitisOptic DiskPapilledemaRetinal DiseasesTomography, Optical Coherence

Identifiers

PMID29176536
PMCPMC5963960
OpenAlexW2769838700

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.