Trial reportJournal of pediatric hematology/oncology2018
Feasibility and Acceptability of Internet-delivered Cognitive Behavioral Therapy for Chronic Pain in Adolescents With Sickle Cell Disease and Their Parents.
Trial report in Journal of pediatric hematology/oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Families' Experiences With Family-Focused Web-Based Interventions for Improving Health: Qualitative Systematic Literature Review.Journal of medical Internet research · 2025Pooled it
- Self-management interventions for children and young people with sickle cell disease: A systematic review.Health expectations : an international journal of public participation in health care and health policy · 2023Pooled it
- Interventions for treating neuropathic pain in people with sickle cell disease.The Cochrane database of systematic reviews · 2019Pooled it
- Psychological therapies (remotely delivered) for the management of chronic and recurrent pain in children and adolescents.The Cochrane database of systematic reviews · 2019Pooled it
- Experiences With a Multicomponent Digital Behavioral Pain Management Intervention for Adults With Sickle Cell Disease: Qualitative Analysis of the CaRISMA Trial.JMIR human factors · 2025Trial
- Digital cognitive behavioral therapy vs education for pain in adults with sickle cell disease.Blood advances · 2024Trial
- Feasibility of In-Home Virtual Reality for Chronic Pain in Sickle Cell Disease.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2024Trial
- Feasibility and preliminary efficacy of the Balance Program to reduce pain-related disability in pediatric sickle cell disease.Pediatric blood & cancer · 2023Trial
- Characterizing User Engagement With a Digital Intervention for Pain Self-management Among Youth With Sickle Cell Disease and Their Caregivers: Subanalysis of a Randomized Controlled Trial.Journal of medical Internet research · 2022Trial
- The effect of a smartphone-based pain management application on pain intensity and quality of life in adolescents with chronic pain.Scientific reports · 2021Trial
- Feasibility of implementing mobile technology-delivered mental health treatment in routine adult sickle cell disease care.Translational behavioral medicine · 2020Trial
- Preliminary Benefits of In-Home Virtual Reality for Chronic Pain in Sickle Cell Disease: Pilot Randomized Trial.Biomedicines · 2026Article
- Article
- Coping Skills, Hospitalizations, and Hopefulness in Youths with Sickle Cell Disease Treated in a Regional Outpatient Comprehensive Pediatric Center.Children (Basel, Switzerland) · 2026Article
- Chronic diseases and depressive symptoms in China: a psychosocial mechanism perspective.Frontiers in public health · 2025Article
- Barriers and facilitators to implementing a task-sharing mental health intervention for Sickle Cell Disease populations in low- and middle-income countries: a qualitative analysis using the Consolidated Framework for Implementation Research (CFIR).Frontiers in public health · 2025Article
- Knowledge and Experience of In-Home Virtual Reality for Chronic Pain in Sickle Cell Disease.The journal of pain · 2024Article
- Internet-Delivered Cognitive Behavioral Treatment for Chronic Pain in Adolescent Survivors of Childhood Cancer: Protocol for a Single-Group Feasibility Trial.JMIR research protocols · 2023Article
- Tailoring a Digital Mental Health Program for Patients With Sickle Cell Disease: Qualitative Study.JMIR mental health · 2023Article
- The management of chronic pain in sickle cell disease: an interview with Nadine Matthie.Pain management · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Pain is a clinical hallmark of sickle cell disease (SCD), and is rarely optimally managed. Cognitive-behavioral therapy (CBT) for pain has been effectively delivered through the Internet in other pediatric populations. We tested feasibility and acceptability of an Internet-delivered CBT intervention in 25 adolescents with SCD (64% female, mean age=14.8 y) and their parents randomized to Internet CBT (n=15) or Internet Pain Education (n=10). Participants completed pretreatment/posttreatment measures. Eight dyads completed semistructured interviews to evaluate treatment acceptability. Feasibility indicators included recruitment and participation rates, engagement and adherence to intervention, and completion of outcome measures. In total, 87 referrals were received from 9 study sites; our recruitment rate was 60% from those families approached for screening. Among participants, high levels of initial intervention engagement (>90%), and adherence (>70%) were demonstrated. Most participants completed posttreatment outcome and diary measures (>75%). Retention at posttreatment was 80%. High treatment acceptability was reported in interviews. Our findings suggest that Internet-delivered CBT for SCD pain is feasible and acceptable to adolescents with SCD and their parents. Engagement and adherence were good. Next steps are to modify recruitment plans to enhance enrollment and determine efficacy of Internet CBT for SCD pain in a large multisite randomized controlled trial.
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