ArticleJournal of epidemiology and community health2018
High percentage of undiagnosed HIV cases within a hyperendemic South African community: a population-based study.
Article in Journal of epidemiology and community health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and predictors of medical information avoidance: a systematic review and meta-analysis.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025Pooled it
- Population impacts of conditional financial incentives and a male-targeted digital decision support application on the HIV treatment cascade in rural KwaZulu Natal: findings from the HITS cluster randomized clinical trial.Journal of the International AIDS Society · 2024Trial
- Home-Based Intervention to Test and Start (HITS): a community-randomized controlled trial to increase HIV testing uptake among men in rural South Africa.Journal of the International AIDS Society · 2021Trial
- Association between tobacco smoking and prevalence of HIV, tuberculosis, hypertension and diabetes in rural South Africa: a cross-sectional study.BMC public health · 2024Article
- Cost-effectiveness of single-visit cervical cancer screening in KwaZulu-Natal, South Africa: a model-based analysis accounting for the HIV epidemic.Frontiers in oncology · 2024Article
- Assessment of standard HIV testing services delivery to injured persons seeking emergency care in Nairobi, Kenya: A prospective observational study.PLOS global public health · 2022Article
- The geography and inter-community configuration of new sexual partnership formation in a rural South African population over fourteen years (2003-2016).PLOS global public health · 2022Article
- Understanding the Reasons for Deferring ART Among Patients Diagnosed Under the Same-Day-ART Policy in Johannesburg, South Africa.AIDS and behavior · 2021Article
- Large age shifts in HIV-1 incidence patterns in KwaZulu-Natal, South Africa.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Prevalence and Risk Factors forOpen forum infectious diseases · 2021Article
- Development and Acceptability of a Tablet-Based App to Support Men to Link to HIV Care: Mixed Methods Approach.JMIR mHealth and uHealth · 2020Article
- Analysis of HIV/AIDS Epidemic and Socioeconomic Factors in Sub-Saharan Africa.Entropy (Basel, Switzerland) · 2020Article
- Understanding Engagement in HIV Programmes: How Health Services Can Adapt to Ensure No One Is Left Behind.Current HIV/AIDS reports · 2020Review
- HIV incidence declines in a rural South African population: a G-imputation approach for inference.BMC public health · 2020Article
- Migration and first-year maternal mortality among HIV-positive postpartum women: A population-based longitudinal study in rural South Africa.PLoS medicine · 2020Article
- The relationships between cognitive function, literacy and HIV status knowledge among older adults in rural South Africa.Journal of the International AIDS Society · 2020Article
- HIV seroconcordance among heterosexual couples in rural KwaZulu-Natal, South Africa: a population-based analysis.Journal of the International AIDS Society · 2020Article
- Home-based intervention to test and start (HITS) protocol: a cluster-randomized controlled trial to reduce HIV-related mortality in men and HIV incidence in women through increased coverage of HIV treatment.BMC public health · 2019Article
- The effect of interventions on the transmission and spread of HIV in South Africa: a phylodynamic analysis.Scientific reports · 2019Article
- Tracking external introductions of HIV using phylodynamics reveals a major source of infections in rural KwaZulu-Natal, South Africa.Virus evolution · 2018Article
Corrections and comments
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Authors and funding
5 authors.
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Abstract
backgroundUndiagnosed HIV infections could undermine efforts to reverse the global AIDS epidemic by 2030. In this study, we estimated the percentage of HIV-positive persons who remain undiagnosed within a hyperendemic South African community.
methodsThe data come from a population-based surveillance system located in the Umkhanyakude district of the northern KwaZulu-Natal province, South Africa. We annually tested 38 661 adults for HIV between 2005 and 2016. Using the HIV-positive test results of 12 039 (31%) participants, we then back-calculated the incidence of infection and derived the number of undiagnosed cases from this result.
resultsThe percentage of undiagnosed HIV cases decreased from 29.3% in 2005 to 15.8% in 2011. During this period, however, approximately 50% of the participants refused to test for HIV, which lengthened the average time from infection to diagnosis. Consequently, the percentage of undiagnosed HIV cases reversed direction and steadily increased from 16.1% to 18.9% over the 2012-2016 period.
conclusionsResults from this hyperendemic South African setting show that the HIV testing rate is low, with long infection times, and an unsatisfactorily high percentage of undiagnosed cases. A high level of repeat HIV testing is needed to minimise the time from infection to diagnosis if the global AIDS epidemic is to be reversed within the next two decades.
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