ArticleDevelopmental cognitive neuroscience2017
White matter structural connectivity and episodic memory in early childhood.
Article in Developmental cognitive neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Foundational Number Sense Training Gains Are Predicted by Hippocampal-Parietal Circuits.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Pooled it
- Executive function after childhood cancer: Insights from network neuroscience.Neuro-oncology advances · 2026Review
- Complementary white matter networks support flexible concept learning.Frontiers in neuroscience · 2026Article
- In Vivo Quantification of White Matter Pathways in the Human Hippocampus.Human brain mapping · 2025Article
- The developmental trajectory of 1H-MRS brain metabolites from childhood to adulthood.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Maternal Diet Quality during Pregnancy Is Associated with Neonatal Brain White Matter Development.Nutrients · 2023Article
- Volumetric development of hippocampal subfields and hippocampal white matter connectivity: Relationship with episodic memory.Developmental psychobiology · 2022Article
- The fornix supports episodic memory during childhood.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Maturity of white matter tracts is associated with episodic memory recall during development.Cerebral cortex communications · 2022Article
- Intrinsic hippocampal functional connectivity underlying rigid memory in children and adolescents with autism spectrum disorder: A case-control study.Autism : the international journal of research and practice · 2021Article
- Tract Specificity of Age Effects on Diffusion Tensor Imaging Measures of White Matter Health.Frontiers in aging neuroscience · 2021Article
- Frontostriatal White Matter Integrity Relations with "Cool" and "Hot" Self-Regulation after Pediatric Traumatic Brain Injury.Journal of neurotrauma · 2021Article
- Article
- Dissecting the Fornix in Basic Memory Processes and Neuropsychiatric Disease: A Review.Brain connectivity · 2020Review
- Empirical Evidence Supporting Neural Contributions to Episodic Memory Development in Early Childhood: Implications for Childhood Amnesia.Child development perspectives · 2020Article
- White matter microstructure mediates the association between physical fitness and cognition in healthy, young adults.Scientific reports · 2019Article
- Early-Life Exposure to the Chinese Famine and Risk of Cognitive Decline.Journal of clinical medicine · 2019Article
- Hippocampal Maturation Drives Memory from Generalization to Specificity.Trends in cognitive sciences · 2018Review
- Three-Dimensional Probabilistic Maps of Mesial Temporal Lobe Structures in Children and Adolescents' Brains.Frontiers in neuroanatomy · 2018Article
Corrections and comments
- Erratum issuedErratum.2020
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Episodic memory undergoes dramatic improvement in early childhood; the reason for this is poorly understood. In adults, episodic memory relies on a distributed neural network. Key brain regions that supporting these processes include the hippocampus, portions of the parietal cortex, and portions of prefrontal cortex, each of which shows different developmental profiles. Here we asked whether developmental differences in the axonal pathways connecting these regions may account for the robust gains in episodic memory in young children. Using diffusion weighted imaging, we examined whether white matter connectivity between brain regions implicated in episodic memory differed with age, and were associated with memory performance differences in 4- and 6-year-old children. Results revealed that white matter connecting the hippocampus to the inferior parietal lobule significantly predicted children's performance on episodic memory tasks. In contrast, variation in the white matter connecting the hippocampus to the medial prefrontal cortex did not relate to memory performance. These findings suggest that structural connectivity between the hippocampus and lateral parietal regions is relevant to the development of episodic memory.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.