Evidence map›Paper›PMID 29174765›Full record

Trial reportPsychiatry research. Neuroimaging2018

Attention training modulates resting-state neurophysiological abnormalities in posttraumatic stress disorder.

Amy Badura-Brack, Timothy J McDermott, Katherine M Becker, Tara J Ryan, Maya M Khanna, Daniel S Pine, Yair Bar-Haim, Elizabeth Heinrichs-Graham, Tony W Wilson

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychiatry research. Neuroimaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Oscillatory brain dynamics underlying affective face processing.Social cognitive and affective neuroscience · 2025
    Article
  3. Article
  4. Article
  5. PTSD as a Public Mental Health Priority.Current psychiatry reports · 2019
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Amy Badura-BrackDepartment of Psychology, Creighton University, 2500 California Plaza, Omaha, NE 68178, USA. Electronic address: amybadurabrack@creighton.edu.
Timothy J McDermottDepartment of Psychology, Creighton University, 2500 California Plaza, Omaha, NE 68178, USA; Center for Magnetoencephalography (MEG), University of Nebraska Medical Center (UNMC), Omaha, NE, USA.
Katherine M BeckerCenter for Magnetoencephalography (MEG), University of Nebraska Medical Center (UNMC), Omaha, NE, USA; Department of Psychology, Colorado State University, Fort Collins, CO, USA.
Tara J RyanDepartment of Psychology, Creighton University, 2500 California Plaza, Omaha, NE 68178, USA; Department of Psychology, Simon Fraser University, Burnaby, BC, Canada.
Maya M KhannaDepartment of Psychology, Creighton University, 2500 California Plaza, Omaha, NE 68178, USA.
Daniel S PineIntramural Research Program, National Institute of Mental Health, Bethesda, MD, USA.
Yair Bar-HaimSchool of Psychological Sciences, Tel Aviv University, Tel Aviv, Israel; The Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.
Elizabeth Heinrichs-GrahamCenter for Magnetoencephalography (MEG), University of Nebraska Medical Center (UNMC), Omaha, NE, USA; Department of Neurological Sciences, UNMC, Omaha, NE, USA.
Tony W WilsonCenter for Magnetoencephalography (MEG), University of Nebraska Medical Center (UNMC), Omaha, NE, USA; Department of Neurological Sciences, UNMC, Omaha, NE, USA.
Creighton University · USUniversity of Nebraska Medical Center · USColorado State University · USNational Institute of Mental Health · USTel Aviv University · IL

Funding

fMRI Studies Of Pediatric Mood And Anxiety DisordersZIAMH002781 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PINE, DANIEL · 2009 to 2025
$41.5M
Fmri Studies Of Risk For Mood And Anxiety Disorders In ChildrenZIAMH002782 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PINE, DANIEL · 2009 to 2025
$28.3M
Neurophysiological markers of HAND and the impact of aging: Evidence from MEGR01MH103220 · NIMH · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WILSON, TONY W · 2014 to 2018
$2.5M
NIMH NIH HHS R01 MH103220
6 · The paper itself

Abstract

Recent research indicates the relative benefits of computerized attention control treatment (ACT) and attention bias modification treatment (ABMT) for posttraumatic stress disorder (PTSD); however, neural changes underlying these therapeutic effects remain unknown. This study examines how these two types of attention training modulate neurological dysfunction in veterans with PTSD. A community sample of 46 combat veterans with PTSD participated in a randomized double-blinded clinical trial of ACT versus ABMT and 32 of those veterans also agreed to undergo resting-state magnetoencephalography (MEG) recordings. Twenty-four veterans completed psychological and MEG assessments at pre- and post-training to evaluate treatment effects. MEG data were imaged using an advanced Bayesian reconstruction method and examined using statistical parametric mapping. In this report, we focus on the neural correlates and the differential treatment effects observed using MEG; the results of the full clinical trial have been described elsewhere. Our results indicated that ACT modulated occipital and ABMT modulated medial temporal activity more strongly than the comparative treatment. PTSD symptoms decreased significantly from pre- to post-test. These initial neurophysiological outcome data suggest that ACT modulates visual pathways, while ABMT modulates threat-processing regions, but that both are associated with normalizing aberrant neural activity in veterans with PTSD.

Indexed as

AdultAttentional BiasBayes TheoremCombat DisordersDouble-Blind MethodHumansMagnetoencephalographyMaleNervous System MalformationsRestStress Disorders, Post-TraumaticVeteransAttention trainingCorticalMagnetoencephalographyMEGPTSDTreatment

Identifiers

PMID29174765
PMCPMC5741514
OpenAlexW2769175308

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.