SynthesisBrazilian journal of physical therapy
Effective exercise intervention period for improving body function or activity in patients with knee osteoarthritis undergoing total knee arthroplasty: a systematic review and meta-analysis.
Synthesis in Brazilian journal of physical therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Evaluation of the efficacy after Total Knee Arthroplasty by Gait analysis in patients with Knee Osteoarthritis: a meta-analysis.Journal of orthopaedic surgery and research · 2024Pooled it
- Pooled it
- The addition of blood flow restriction to resistance exercise in individuals with knee pain: a systematic review and meta-analysis.Brazilian journal of physical therapyPooled it
- The effect of exercise on clinical pain: a systematic umbrella review and meta-meta-analysis.Pain reports · 2026Article
- Impact of therapeutic exercises on pain-related outcomes in patients with knee osteoarthritis: an umbrella review of 116 systematic reviews.Frontiers in pain research (Lausanne, Switzerland) · 2026Review
- Early Postoperative Rehabilitation Behavior After Total Joint Arthroplasty: A Theory-Informed Qualitative Study.Journal of multidisciplinary healthcare · 2026Article
- Applying the Knowledge-to-Action Framework to Implement and Evaluate an Evidence-Based Functional Exercise Program for Elderly Patients After Total Knee Arthroplasty: A Mixed-Methods Study.Clinical interventions in aging · 2025Article
- An Interactive Vision-Based 3D Augmented Reality System for In-Home Physical Rehabilitation: A Qualitative Inquiry to Inform System Development.Health expectations : an international journal of public participation in health care and health policy · 2024Article
- Effects of Blood Flow Restriction Training in Patients before and after Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2024Review
- Research Trends and Foci in Osteoarthritis Pain from 2012 to 2022: Bibliometric and Visualization Study.Journal of pain research · 2023Article
- Reporting of post-operative rehabilitation interventions for Total knee arthroplasty: a scoping review.BMC musculoskeletal disorders · 2021Article
- Impact of sarcopenia on rehabilitation outcomes after total knee replacement in older adults with knee osteoarthritis.Therapeutic advances in musculoskeletal disease · 2021Article
- Validation of Physical Performance Tests in Individuals with Advanced Knee Osteoarthritis.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2019Article
- Article
- What are the clinical implications of knee crepitus to individuals with knee osteoarthritis? An observational study with data from the Osteoarthritis Initiative.Brazilian journal of physical therapyObservational
- Knee osteoarthritis: key treatments and implications for physical therapy.Brazilian journal of physical therapyReview
- Can muscle weakness and disability influence the relationship between pain catastrophizing and pain worsening in patients with knee osteoarthritis? A cross-sectional study.Brazilian journal of physical therapyArticle
- Predicting physical activity recovery after hip and knee arthroplasty? A longitudinal cohort study.Brazilian journal of physical therapyArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVarious systematic reviews and/or meta-analyses examining the effects of pre- or postoperative exercise on body function or activity in patients undergoing total knee arthroplasty (TKA) have been published. However, the interventional period needed to at least improve outcomes is unknown.
objectiveThe aim of this systematic review and meta-analysis was to investigate the exercise intervention period needed to effectively improve body function or activity before and after TKA in patients with knee osteoarthritis (OA).
methodsStudies published until July 2017 were included in the review. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach was applied to each meta-analysis to determine the quality of the evidence.
resultsTwenty-seven randomized controlled trials were identified. A meta-analysis indicated that exercises performed for 8 weeks after discharge in addition to standard postoperative intervention effectively improved body function as assessed using pain level; physical function, and stiffness on the Western Ontario and McMaster Universities Arthritis Index; extension strength; active knee flexion range of motion; timed up and go test; and gait speed.
conclusionOverall, we found low- to moderate-quality evidence that an 8-week exercise period was needed after discharge to improve body function and activity in patients with knee OA undergoing TKA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.