ArticleJournal of shoulder and elbow surgery2018
Effects of pulsed electromagnetic field therapy at different frequencies and durations on rotator cuff tendon-to-bone healing in a rat model.
Article in Journal of shoulder and elbow surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Efficacy of Pulsed Electromagnetic Fields on Pain, Stiffness, and Physical Function in Osteoarthritis: A Systematic Review and Meta-Analysis.Pain research & management · 2022Pooled it
- The promising regenerative potential of pulsed electromagnetic fields toward tendon differentiation : a hamstring tendon explant culture study.Bone & joint research · 2026Article
- Active vs. sham pulsed electromagnetic field therapy added to standardized conservative care for partial-thickness supraspinatus tears: study protocol for a randomized, assessor-blinded, sham-controlled trial.Frontiers in sports and active living · 2026Article
- Bilayer book- like decellularized extracellular matrix scaffold with bioactive coatings for rotator cuff repair.Materials today. Bio · 2025Article
- Safety and preliminary efficacy of an electrically stimulated implant for mandibular bone regeneration: a pilot study in a large animal model.Clinical oral investigations · 2025Article
- Pulsed electromagnetic field prevents tooth relapse after orthodontic tooth movement in rat models.Journal of Taibah University Medical Sciences · 2025Article
- Gathering Evidence to Leverage Musculoskeletal Magnetic Stimulation Towards Clinical Applicability.Small science · 2024Article
- Positive and Negative Effects of Administering a Magnetic Field to Patients with Rheumatoid Arthritis (RA).Journal of clinical medicine · 2024Article
- Harnessing electromagnetic fields to assist bone tissue engineering.Stem cell research & therapy · 2023Review
- Pulsed electromagnetic field therapy alters early healing in a rat model of rotator cuff injury and repair: Potential mechanisms.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022Article
- Pulsed Electromagnetic Field Stimulators Efficacy for Noninvasive Bone Growth in Spine Surgery.Journal of Korean Neurosurgical Society · 2021Article
- Effects of focused continuous pulsed electromagnetic field therapy on early tendon-to-bone healing.Bone & joint research · 2021Article
- Article
- Pulsed electromagnetic fields improve the healing process of Achilles tendinopathy: a pilot study in a rat model.Bone & joint research · 2020Article
- In Vitro Production of Calcified Bone Matrix onto Wool Keratin Scaffolds via Osteogenic Factors and Electromagnetic Stimulus.Materials (Basel, Switzerland) · 2020Article
- A2A adenosine receptors are involved in the reparative response of tendon cells to pulsed electromagnetic fields.PloS one · 2020Article
- Effects of Pulsed Electromagnetic Field Therapy on Rat Achilles Tendon Healing.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020Article
- Pulsed electromagnetic fields reduce acute inflammation in the injured rat-tail intervertebral disc.JOR spine · 2019Article
- Global Responses of Il-1β-Primed 3D Tendon Constructs to Treatment with Pulsed Electromagnetic Fields.Cells · 2019Article
- Pulsed Electromagnetic Fields Improve Tenogenic Commitment of Umbilical Cord-Derived Mesenchymal Stem Cells: A Potential Strategy for Tendon Repair-An In Vitro Study.Stem cells international · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
backgroundRotator cuff tears affect millions of individuals each year, often requiring surgical intervention. However, repair failure remains common. We have previously shown that pulsed electromagnetic field (PEMF) therapy improved tendon-to-bone healing in a rat rotator cuff model. The purpose of this study was to determine the influence of both PEMF frequency and exposure time on rotator cuff healing.
methodsTwo hundred ten Sprague-Dawley rats underwent acute bilateral supraspinatus injury and repair followed by either Physio-Stim PEMF or high-frequency PEMF therapy for 1, 3, or 6 hours daily. Control animals did not receive PEMF therapy. Mechanical and histologic properties were assessed at 4, 8, and 16 weeks.
resultsImprovements in different mechanical properties at various endpoints were identified for all treatment modalities when compared with untreated animals, regardless of PEMF frequency or duration. Of note, 1 hour of Physio-Stim treatment showed significant improvements in tendon mechanical properties across all time points, including increases in both modulus and stiffness as early as 4 weeks. Collagen organization improved for several of the treatment groups compared with controls. In addition, improvements in type I collagen and fibronectin expression were identified with PEMF treatment. An important finding was that no adverse effects were identified in any mechanical or histologic property.
conclusionsOverall, our results suggest that PEMF therapy has a positive effect on rat rotator cuff healing for each electromagnetic fundamental pulse frequency and treatment duration tested in this study.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.