Evidence map›Paper›PMID 29174245›Full record

Trial reportIndian heart journal

Volume-outcome relationships for transcatheter aortic valve replacement-risk-adjusted and volume stratified analysis of TAVR outcomes.

Divya Ratan Verma, Yash Pershad, Mohamad Lazkani, Kenith Fang, Michael Morris, Ashish Pershad

Open access · goldAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. The Impact of Institutional Volume on Transcatheter Aortic Valve Replacement Outcomes.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Divya Ratan VermaDivision of Interventional Cardiology, Banner University Medical Center, United States.
Yash PershadDivision of Cardiac Imaging, Banner University Medical Center, United States.
Mohamad LazkaniDivision of Interventional Cardiology, Banner University Medical Center, United States.
Kenith FangDivision of Cardiothoracic Surgery, Banner University Medical Center, United States.
Michael MorrisDivision of Cardiac Imaging, Banner University Medical Center, United States.
Ashish PershadDivision of Interventional Cardiology, Banner University Medical Center, United States. Electronic address: ashish.pershad@bannerhealth.com.
Banner - University Medical Center Tucson · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis purpose of the study was to evaluate TAVR outcomes at low, intermediate and high volume institutions.

backgroundFor the care of complex patients, volume-outcome effect is well described. The initial US TAVR experience was limited to a few centers of excellence. The impact of institutional volume on outcomes after TAVR has not been systematically studied.

methodsWithin the Banner Health system, TAVR is performed at 3 institutions-a low volume, an intermediate volume and a high volume institution. 181 consecutive patients undergoing TAVR within these 3 institutions were the study cohort. To adjust for bias and confounders between the 3 groups, risk-adjusted multivariate logistic regression and propensity score analysis was performed. The primary endpoint was a composite of mortality, dialysis-dependent renal failure, cerebrovascular accident, need for new permanent pacemaker and readmission within 30days.

resultsThe primary endpoint was reached in 38.8% of patients at the high volume institution and 76.2% of patients at the low volume institution (p<0.01). Having a TAVR procedure at a larger volume institution was an independent predictor of having improved outcomes (OR 0.33, 95% CI 0.16-0.68; p=0.003). These improved outcomes after the TAVR procedure noted at the large volume institution were seen in the most complex patients: age ≥80years, BMI >30, diabetes, hypertension, prior CAD, CKD and NYHA class III/IV heart failure.

conclusionsHigh-risk patients undergoing TAVR at a large volume institution have better 30-day outcomes compared to outcomes at intermediate and low volume centers.

Indexed as

Transcatheter Aortic Valve ReplacementAgedAged, 80 and overAortic Valve StenosisFemaleFollow-Up StudiesHospitals, High-VolumeHospitals, Low-VolumeHumansIncidenceMalePostoperative ComplicationsRetrospective StudiesRisk FactorsSurvival RateTime FactorsHealth-care outcomesInstitutional-volumeTranscatheter-valve-interventions

Identifiers

PMID29174245
PMCPMC5717284
OpenAlexW2611971691

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.