ArticleUltrasound in medicine & biology2018
Effect of Temperature on the Size Distribution, Shell Properties, and Stability of Definity
Article in Ultrasound in medicine & biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 53 citations in OpenAlex.
- Assessment of Cavitation From DEFINITY and DEFINITY RT.Ultrasound in medicine & biology · 2026Article
- Review
- Echo contrast medium: How the use of contrast echocardiography (ultrasound contrast agents) can improve patient care.World journal of methodology · 2025Review
- Mechanical Properties of Medical Microbubbles and Echogenic Liposomes-A Review.Micromachines · 2025Review
- 3D ultrasound localization microscopy of the nonhuman primate brain.EBioMedicine · 2025Article
- Investigation Into the Subharmonic Response of Three Contrast Agents in Static and Dynamic Flow Environments Using a Commercially Available Diagnostic Ultrasound Scanner.Ultrasound in medicine & biology · 2024Article
- Microbubble-enhanced transcranial MR-guided focused ultrasound brain hyperthermia: heating mechanism investigation using finite element method.Ultrasonics sonochemistry · 2024Article
- Efficient ultrasound-mediated drug delivery to orthotopic liver tumors - Direct comparison of doxorubicin-loaded nanobubbles and microbubbles.Journal of controlled release : official journal of the Controlled Release Society · 2024Article
- Article
- Quantitative Pharmacokinetics Reveal Impact of Lipid Composition on Microbubble and Nanoprogeny Shell Fate.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Efficient ultrasound-mediated drug delivery to orthotopic liver tumors - Direct comparison of doxorubicin-loaded nanobubbles and microbubbles.bioRxiv : the preprint server for biology · 2023Article
- Probing the pressure dependence of sound speed and attenuation in bubbly media: Experimental observations, a theoretical model and numerical calculations.Ultrasonics sonochemistry · 2023Article
- Material Properties, Dissolution and Time Evolution of PEGylated Lipid-Shelled Microbubbles: Effects of the Polyethylene Glycol Hydrophilic Chain Configurations.Ultrasound in medicine & biology · 2022Article
- Theranostic Microbubbles with Homogeneous Ligand Distribution for Higher Binding Efficacy.Pharmaceutics · 2022Article
- Nonlinear dynamics and bifurcation structure of ultrasonically excited lipid coated microbubbles.Ultrasonics sonochemistry · 2021Article
- Shell properties and concentration stability of acoustofluidic delivery agents.Physical and engineering sciences in medicine · 2021Article
- Cavitation Emissions Nucleated by Definity Infused through an EkoSonic Catheter in a Flow Phantom.Ultrasound in medicine & biology · 2021Article
- Stability of Engineered Micro or Nanobubbles for Biomedical Applications.Pharmaceutics · 2020Review
- Temporal stability of lipid-shelled microbubbles during acoustically-mediated blood-brain barrier opening.Frontiers in physics · 2020Article
- Ultrasound- and Microbubble-Assisted Gemcitabine Delivery to Pancreatic Cancer Cells.Pharmaceutics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Physical characterization of an ultrasound contrast agent (UCA) aids in its safe and effective use in diagnostic and therapeutic applications. The goal of this study was to investigate the impact of temperature on the size distribution, shell properties, and stability of Definity
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.