ArticleThe Canadian journal of cardiology2017
A Novel Pacing Strategy With Low and Stable Output: Pacing the Left Bundle Branch Immediately Beyond the Conduction Block.
Article in The Canadian journal of cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 7 registered trials, which are not on this map. Cited by 351 papers, 10 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Permanent Left Bundle Branch Area Pacing for Atrioventricular Block
Comparison Between Left Bundle Branch Pacing and Biventricular Pacing for Cardiac Resynchronization Therapy in Heart Failure(LBBP-RESYNC)
Protection on Cardiac Function With Left Bundle Branch Pacing in Patients With Atrioventricular Block(OptimPacing)
Feasibility of Simplified Permanent Left Bundle Branch Pacing (LBBP) Without Electrophysiological Recording System
Left Bundle Branch Pacing as Initial Therapy in Patients With Non-ischemic Heart Failure and Left Bundle Branch Block (LIT-HF Study)
Long-term Efficacy and Safety Research of Left Bundle Branch Pacing
Intracardiac Electrical Characteristics of LBBAP
Who cites it
351 citing papers in PubMed, 10 syntheses or guidelines pooled it, 728 citations in OpenAlex.
- Conduction system pacing for cardiac resynchronization therapy: a systematic review.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Pooled it
- Conduction System Pacing Versus Biventricular Cardiac Resynchronization in HFmrEF: A Systematic Review and Meta-Analysis.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026Pooled it
- Efficacy and safety of conduction system pacing in heart failure patients with non-left bundle branch block morphology: a systematic review and meta-analysis.Frontiers in physiology · 2025Pooled it
- Stylet-driven leads compared with lumenless leads for left bundle branch area pacing: a systematic review and meta-analysis.BMC cardiovascular disorders · 2024Pooled it
- Clinical Outcomes of Left Bundle Branch Area Pacing Compared with Biventricular Pacing in Patients with Heart Failure Requiring Cardiac Resynchronization Therapy: Systematic Review and Meta-Analysis.Reviews in cardiovascular medicine · 2023Pooled it
- 2023 HRS/APHRS/LAHRS guideline on cardiac physiologic pacing for the avoidance and mitigation of heart failure.Heart rhythm · 2023Guideline
- Risk of Atrial Fibrillation Following Left Bundle Branch Area Pacing versus Right Ventricular Pacing and Biventricular Pacing: A Systematic Review and Meta-Analysis.Reviews in cardiovascular medicine · 2023Pooled it
- His-Purkinje system pacing versus biventricular pacing in clinical efficacy: a systematic review and meta-analysis.BMC cardiovascular disorders · 2023Pooled it
- Conduction system pacing is superior to biventricular pacing in patients with heart failure: Insights from the pooled clinical studies.Frontiers in physiology · 2023Pooled it
- Pooled it
- Long-Term Outcomes of Left Bundle-Branch Pacing vs Biventricular Pacing in Heart Failure: The HeartSync-LBBP Randomized Clinical Trial.JAMA cardiology · 2026Trial
- Stepwise application of ECG and electrogram-based criteria to ensure electrical resynchronization with left bundle branch pacing.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Trial
- Conduction system pacing, a European survey: insights from clinical practice.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Trial
- Left Bundle Branch Area Pacing in Heart Failure: A Physiological Alternative to Conventional Biventricular Cardiac Resynchronization Therapy and a Step Towards Personalized Device Therapy.Journal of personalized medicine · 2026Review
- When the helix unwinds: Lead entrapment during left bundle branch area pacing.HeartRhythm case reports · 2026Article
- Lead-Site Myocardial Scar Predicts Echocardiographic Response to Left Bundle Branch Area Pacing.Pacing and clinical electrophysiology : PACE · 2026Article
- Innovations in cardiac device therapy in the era of advanced rhythm management: implantable defibrillators and conduction system pacing.Heart (British Cardiac Society) · 2026Review
- Sex-Based Differences in Left Bundle Branch Capture During Left Bundle Branch Area Pacing.Pacing and clinical electrophysiology : PACE · 2026Article
- Electrophysiologic Assessment of the Successful Left Bundle Branch Pacing Using the Standardized Criteria.Journal of cardiovascular electrophysiology · 2026Article
- Delayed Stimulus to V6 R-Wave Peak Time for Selective Left Bundle Branch Pacing: Characteristics and Underlying Mechanisms.CJC open · 2026Article
291 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This report demonstrates the feasibility of pacing the left bundle branch (LBB) immediately beyond the conduction block to functionally restore the impaired His-Purkinje conduction system in a patient with heart failure and left bundle branch block (LBBB). The pacing required only a low pacing output (0.5 volts/0.5 ms) to correct the LBBB with accompanying right BBB on the electrocardiogram. Over 1-year of follow-up, the patient had a significant improvement in clinical outcome and echocardiographic measurements. The case shows a novel pacing strategy for patients with BBB that affects many patients with heart failure.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.