Evidence map›Paper›PMID 29173522›Full record

ReviewGastroenterology clinics of North America2017

Vitamins and Minerals in Inflammatory Bowel Disease.

Fayez K Ghishan, Pawel R Kiela

Open access · greenAbstract readReview
In one paragraph

Review in Gastroenterology clinics of North America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 6 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 6 syntheses or guidelines pooled it, 135 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Pooled it
  5. Risk Factors for Vitamin D Deficiency in Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2021
    Pooled it
  6. Diet and inflammatory bowel disease: The Asian Working Group guidelines.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2019
    Guideline
  7. Trial
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Understanding the therapeutic toolkit for inflammatory bowel disease.Nature reviews. Gastroenterology & hepatology · 2025
    Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Fayez K GhishanDepartment of Pediatrics, University of Arizona, Tucson, AZ, USA.
Pawel R KielaDepartment of Pediatrics, University of Arizona, Tucson, AZ, USA; Department of Immunobiology, University of Arizona, Tucson, AZ, USA. Electronic address: pkiela@peds.arizona.edu.
University of Arizona · US

Funding

DEVELOPMENT OF INTESTINAL ION TRANSPORTR01DK041274 · NIDDK · VANDERBILT UNIVERSITY · PI GHISHAN, FAYEZ KHALAF, KIELA, PAWEL R · 1988 to 2016
$5.5M
DEVELOPMENT OF INTESTINAL TRANSPORT OF CA++ AND PIR37DK033209 · NIDDK · UNIVERSITY OF ARIZONA · PI GHISHAN, FAYEZ KHALAF · 1995 to 2017
$4.7M
INTESTINAL TRANSPORT OF CALCIUM AND PHOSPHATIDYLINOSITOLR01DK033209 · NIDDK · VANDERBILT UNIVERSITY · PI GHISHAN, FAYEZ KHALAF · 1986 to 2007
$1.8M
Modulation of dendritic cell function in the pathogenesis of Inflammatory Bowel DiseasesR01DK109711 · NIDDK · UNIVERSITY OF ARIZONA · PI GHISHAN, FAYEZ KHALAF, KIELA, PAWEL R · 2016 to 2020
$1.7M
NIDDK NIH HHS R01 DK033209NIDDK NIH HHS R01 DK041274NIDDK NIH HHS R01 DK109711NIDDK NIH HHS R37 DK033209
6 · The paper itself

Abstract

Indiscriminate use of multivitamin/mineral supplements in the general population may be misguided, but patients with chronic Inflammatory Bowel Diseases (IBD) should be monitored and compensated for nutritional deficiencies. Mechanistic links between vitamin/mineral deficiencies and IBD pathology has been found for some micronutrients and normalizing their levels is clinically beneficial. Others, like vitamin A, although instinctively desirable, produced disappointing results. Restoring normal levels of the selected micronutrients requires elevated doses to compensate for defects in absorptive or signaling mechanisms. This article describes some aspects of vitamin and mineral deficiencies in IBD, and summarizes pros and cons of supplementation.

Indexed as

Anemia, Iron-DeficiencyAnimalsAvitaminosisBiotinCalciumCholecalciferolDietary SupplementsFolic AcidHumansInflammatory Bowel DiseasesIronThiamineVitamin AVitamin B 12Vitamin B 6Vitamin KBiotinCalciumCholecalciferolFolic AcidIronThiamineVitamin AVitamin B 12Vitamin B 6Vitamin KVitaminsZincCrohn diseaseDeficiencyDietNutritionSupplementationUlcerative colitis

Identifiers

PMID29173522
PMCPMC6342481
OpenAlexW2761519182

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.