Evidence map›Paper›PMID 29173517›Full record

ReviewGastroenterology clinics of North America2017

Complementary and Alternative Medicine Strategies for Therapeutic Gut Microbiota Modulation in Inflammatory Bowel Disease and their Next-Generation Approaches.

Abigail R Basson, Minh Lam, Fabio Cominelli

Open access · greenAbstract readReview
In one paragraph

Review in Gastroenterology clinics of North America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

  1. mBio · 2025
    Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Nutrients · 2021
    Review
  10. Evaluation of anFrontiers in microbiology · 2021
    Article
  11. Article
  12. Review
  13. Review
  14. Cannabinoids and Opioids in the Treatment of Inflammatory Bowel Diseases.Clinical and translational gastroenterology · 2020
    Review
  15. Deficiency of Dietary Fiber inCanadian journal of gastroenterology & hepatology · 2019
    Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Abigail R BassonDigestive Health Research Institute, Case Western Reserve University, Cleveland, OH, USA; Department of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Minh LamDigestive Health Research Institute, Case Western Reserve University, Cleveland, OH, USA; Department of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Fabio CominelliDigestive Health Research Institute, Case Western Reserve University, Cleveland, OH, USA; Department of Medicine, Case Western Reserve University, Cleveland, OH, USA; Department of Pathology, Case Western Reserve University, Cleveland, OH, USA. Electronic address: Fabio.Cominelli@uhhospitals.org.
Case Western Reserve University · US

Funding

Ubiquitination Pathways Mediating Chronic Intestinal InflammationP01DK091222 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI RODRIGUEZ-PALACIOS, ALEXANDER · 2011 to 2020
$16.5M
The Cleveland Digestive Diseases Research Core Center (DDRCC)P30DK097948 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI AMITABH CHAK · 2015 to 2026
$15.6M
MECHANISMS OF EXPERIMENTAL CROHNS DISEASER01DK055812 · NIDDK · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI COMINELLI, FABIO · 1999 to 2019
$4.9M
CYTOKINES AND INFLAMMATORY BOWEL DISEASER01DK042191 · NIDDK · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI COMINELLI, FABIO, PIZARRO, THERESA TORRES · 1995 to 2022
$4.7M
CYTOKINES AND INFLAMMATORY BOWEL DISEASER37DK042191 · NIDDK · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI COMINELLI, FABIO · 1999 to 2009
$3.8M
Combined Training Program in Digestive Disease SciencesT32DK083251 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI COMINELLI, FABIO, FIOCCHI, CLAUDIO · 2010 to 2025
$3.6M
Cytokines and Inflammatory Bowel DiseaseR56DK042191 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI COMINELLI, FABIO · 2010 to 2010
$504k
Mechanisms of Experimental Crohn's DiseaseR56DK055812 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI COMINELLI, FABIO, RODRIGUEZ-PALACIOS, ALEXANDER · 2021 to 2021
$403k
NIDDK NIH HHS P01 DK091222NIDDK NIH HHS P30 DK097948NIDDK NIH HHS R01 DK042191NIDDK NIH HHS R01 DK055812NIDDK NIH HHS R37 DK042191NIDDK NIH HHS R56 DK042191NIDDK NIH HHS R56 DK055812NIDDK NIH HHS T32 DK083251
6 · The paper itself

Abstract

The human gut microbiome exerts a major impact on human health and disease, and therapeutic gut microbiota modulation is now a well-advocated strategy in the management of many diseases, including inflammatory bowel disease (IBD). Scientific and clinical evidence in support of complementary and alternative medicine, in targeting intestinal dysbiosis among patients with IBD, or other disorders, has increased dramatically over the past years. Delivery of "artificial" stool replacements for fecal microbiota transplantation (FMT) could provide an effective, safer alternative to that of human donor stool. Nevertheless, optimum timing of FMT administration in IBD remains unexplored, and future investigations are essential.

Indexed as

Complementary TherapiesDietDietary SupplementsGastrointestinal MicrobiomeAnimalsCaseinsFecal Microbiota TransplantationHumansInflammatory Bowel DiseasesMedical MarijuanaPeptide FragmentsPhytochemicalsPolysaccharidesPrebioticsProbioticsPsychophysiologycaseinomacropeptideCaseinsMedical MarijuanaPeptide FragmentsPhytochemicalsPolysaccharidesPrebioticsComplementary and alternative medicineCrohn diseaseGut microbiotaInflammatory bowel diseaseNext-generationNutraceuticalsUlcerative colitis

Identifiers

PMID29173517
PMCPMC5909826
OpenAlexW2768322854

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.