ArticleJournal of feline medicine and surgery2018
Insulin-like growth factor type 1 concentrations in hyperthyroid cats before and after treatment with thiamazole.
Article in Journal of feline medicine and surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 7 citations in OpenAlex.
- Change in insulin-like growth factor type 1 concentration after radioactive iodine treatment in cats with hyperthyroidism.Journal of feline medicine and surgery · 2025Article
- Growth hormone-secreting pituitary adenoma combined with Graves' disease: retrospective case series and literature review.Endocrine connections · 2024Article
- Feline Comorbidities: Hypersomatotropism-induced diabetes in cats.Journal of feline medicine and surgery · 2024Review
- Teprotumumab-associated chronic hearing loss screening and proposed treatments.BMJ case reports · 2022Article
- Observational
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives The aim of this study was to evaluate changes in circulating insulin-like growth factor type 1 (IGF-1) concentrations in hyperthyroid cats, before and after thiamazole treatment. Methods Thirty-four hyperthyroid cats were retrospectively included. Plasma free thyroxine (fT4) and IGF-1 concentrations were measured at diagnosis and 3 months after initiating antithyroid drug therapy. Results Median fT4 significantly decreased ( P <0.001) after treatment (from 78 pmol/l [range 43-122 pmol/l] to 31 pmol/l [range below assay limit of detection to 88 pmol/l]), whereas IGF-1 values significantly increased ( P <0.001) after treatment (from 117 ng/ml [33-341 ng/ml] to 221 ng/ml [36-865 ng/ml]). fT4 and IGF-1 concentrations were significantly negatively correlated both at diagnosis (r = -0.43, P = 0.01) and after treatment (r = -0.51, P = 0.002). Conclusions and relevance In cats, IGF-1 concentrations appear to be inversely proportional to the severity of hyperthyroidism and significantly increase after treatment with thiamazole.
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