ArticleAmerican journal of respiratory and critical care medicine2018
Identification of Diagnostic Criteria for Chronic Hypersensitivity Pneumonitis: An International Modified Delphi Survey.
Article in American journal of respiratory and critical care medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 6 of them syntheses that pooled it.
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Who cites it
104 citing papers in PubMed, 6 syntheses or guidelines pooled it, 235 citations in OpenAlex.
- Bronchoalveolar lavage lymphocyte patterns in hypersensitivity pneumonitis and nonspecific interstitial pneumonia: a systematic review.Frontiers in medicine · 2026Pooled it
- Diagnosis and Treatment of Hypersensitivity Pneumonitis: S2k Guideline of the German Respiratory Society and the German Society for Allergology and Clinical Immunology.Respiration; international review of thoracic diseases · 2025Guideline
- Occupational causes of hypersensitivity pneumonitis: a systematic review and compendium.Occupational medicine (Oxford, England) · 2021Pooled it
- Diagnosis of Hypersensitivity Pneumonitis in Adults. An Official ATS/JRS/ALAT Clinical Practice Guideline.American journal of respiratory and critical care medicine · 2020Guideline
- Desquamative interstitial pneumonia: a systematic review of its features and outcomes.European respiratory review : an official journal of the European Respiratory Society · 2020Pooled it
- A Systematically Derived Exposure Assessment Instrument for Chronic Hypersensitivity Pneumonitis.Chest · 2020Pooled it
- Study of nasal mucosa histopathological changes in patients with hypersensitivity pneumonitis.Scientific reports · 2023Trial
- Consensus-based radiographic threshold for identifying vertical periodontal bone loss: an international observer study.Scientific reports · 2026Article
- Utilization Patterns of Nebulized Glycopyrronium in Patients Hospitalized for Acute Exacerbations of Obstructive Airway Disease (AEOAD)-Indian Expert Perspectives.Advances in respiratory medicine · 2026Article
- Dual pathology, dual burden: Functional impact of emphysema and fibrosis in Hypersensitivity Pneumonitis.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2026Article
- Transbronchial lung cryobiopsy in fibrotic hypersensitivity pneumonitis: prognostic differences and intra-lobar variability.BMC pulmonary medicine · 2026Article
- Impact of older age on prognosis in hypersensitivity pneumonitis: A systematic review and meta-analysis.Experimental and therapeutic medicine · 2026Article
- Current concepts in the diagnosis and treatment of hypersensitivity pneumonitis: a narrative review.Respiratory research & clinical practice · 2026Review
- Korean Guidelines for the Diagnosis and Management of Interstitial Lung Diseases: Hypersensitivity Pneumonitis.Tuberculosis and respiratory diseases · 2025Article
- Prognostic significance of acute exacerbations and usual interstitial pneumonia in fibrotic interstitial lung disease.Scientific reports · 2025Article
- Endovascular treatment of peripheral arterial disease: Endo-STAR framework for the design, conduct, and reporting of trials.The British journal of surgery · 2025Article
- Hypersensitivity pneumonitis associated with home mold exposure: A retrospective cohort analysis.PloS one · 2025Article
- Frequency of imaging phenotypes of pulmonary interstitial fibrosis.SA journal of radiology · 2025Article
- Outcomes and predictors of progression in progressive pulmonary fibrosis.Annals of medicine · 2024Article
- Correlation of CT-based radiomics analysis with pathological cellular infiltration in fibrosing interstitial lung diseases.Japanese journal of radiology · 2024Article
44 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
Abstract
rationaleCurrent diagnosis of chronic hypersensitivity pneumonitis (cHP) involves considering a combination of clinical, radiological, and pathological information in multidisciplinary team discussions. However, this approach is highly variable with poor agreement between centers.
objectivesWe aimed to identify diagnostic criteria for cHP that reach consensus among international experts.
methodsA 3-round modified Delphi survey was conducted between April and August 2017. Forty-five experts in interstitial lung disease from 14 countries participated in the online survey. Diagnostic items included in round 1 were generated using expert interviews and literature review. During rounds 1 and 2, experts rated the importance of each diagnostic item on a 5-point Likert scale. The a priori threshold of consensus was ≥ 75% of experts rating a diagnostic item as very important or important. In the third round, experts graded the items that met consensus as important and provided their level of diagnostic confidence for a series of clinical scenarios. MEASUREMENTS AND MAIN
resultsConsensus was achieved on 18 of the 40 diagnostic items. Among these, experts gave the highest level of importance to the identification of a causative antigen, time relation between exposure and disease, mosaic attenuation on chest imaging, and poorly formed non-necrotizing granulomas on pathology. In clinical scenarios, the diagnostic confidence of experts in cHP was heightened by the presence of these diagnostic items.
conclusionThis consensus-based approach for the diagnosis of cHP represents a first step towards the development of international guidelines for the diagnosis of cHP.
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