Evidence map›Paper›PMID 29172401›Full record

ArticleThe Korean journal of internal medicine2018

Management of carbapenem-resistant Acinetobacter baumannii epidemic in an intensive care unit using multifaceted intervention strategy.

Jeongmin Hong, Ok Jeom Jang, Mi Hui Bak, Eun Hwa Baek, Ki-Ho Park, Sun In Hong, Oh-Hyun Cho, In-Gyu Bae

Open access · goldAbstract read
In one paragraph

Article in The Korean journal of internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Control of Healthcare-Associated Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2022
    Article
  5. Article
  6. Review
  7. Carbapenem-resistantFrontiers in microbiology · 2022
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jeongmin HongDepartment of Internal Medicine, Gyeongsang National University Hospital, Jinju, Korea.
Ok Jeom JangInfection Control Office, Gyeongsang National University Hospital, Jinju, Korea.
Mi Hui BakInfection Control Office, Gyeongsang National University Hospital, Jinju, Korea.
Eun Hwa BaekInfection Control Office, Gyeongsang National University Hospital, Jinju, Korea.
Ki-Ho ParkDepartment of Internal Medicine, Kyung Hee University Hospital, Seoul, Korea.
Sun In HongDepartment of Internal Medicine, Gyeongsang National University Changwon Hospital, Changwon, Korea.
Oh-Hyun ChoDepartment of Internal Medicine, Gyeongsang National University Hospital, Jinju, Korea.
In-Gyu BaeDepartment of Internal Medicine, Gyeongsang National University Hospital, Jinju, Korea.
Gyeongsang National University Hospital · KRChangwon National University · KRGyeongsang National University · KRKyung Hee University Dental Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsWe evaluated the effects of a multifaceted intervention for controlling a carbapenem-resistant Acinetobacter baumannii (CRAB) epidemic in an intensive care unit (ICU) with no restrictions on carbapenem use.

methodsThis study was conducted in a medical ICU between April 2012 and June 2016. The baseline infection control programs included surveillance cultures, contact precautions, and environmental cleaning. However, increases in the detection of CRAB isolates beginning in May 2013 led to the implementation of a new protocol, consisting of universal glove and gown use with daily chlorhexidine bathing for all patients in combination with baseline programs. The efficacy of the intervention was subjected to interrupted time series (ITS) analysis.

resultsThe multifaceted intervention led to a decrease in the incidence of CRAB from 17.65 to 0.89 cases per 1,000 patient-days, during the study period (p < 0.001). ITS analysis revealed a significant change in the trend of CRAB incidence (-0.413, p < 0.001). Over this same period, mean monthly use of carbapenems increased from 143.54 ± 95.73 to 204.95 ± 78.43 doses per 1,000 patient-days (p = 0.018).

conclusionOur multifaceted intervention reduced the incidence of CRAB acquisition in an ICU where carbapenem use was not restricted.

Indexed as

Acinetobacter InfectionsAnti-Bacterial AgentsCarbapenemsDrug Resistance, BacterialIntensive Care UnitsAcinetobacter baumanniiAgedCross InfectionDisease OutbreaksFemaleHumansMaleMiddle AgedRepublic of KoreaRetrospective StudiesAnti-Bacterial AgentsCarbapenemsAcinetobacter baumanniiCarbapenem resistanceChlorhexidineIntensive care units

Identifiers

PMID29172401
PMCPMC6129627
OpenAlexW2769615859

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.