Evidence map›Paper›PMID 29171095›Full record

ReviewJournal of veterinary internal medicine2018

The Gastrointestinal Microbiome: A Review.

P C Barko, M A McMichael, K S Swanson, D A Williams

Open access · goldAbstract readReview
In one paragraph

Review in Journal of veterinary internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 349 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
349citing papers in PubMed, 1 pooled it
22.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

349 citing papers in PubMed, 1 synthesis or guideline pooled it, 781 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. The Effects ofMicroorganisms · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. An Ecological Framework for Interpreting the Canine Gut Microbiome.Animals : an open access journal from MDPI · 2026
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review

289 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

P C BarkoVeterinary Clinical Medicine, University of Illinois at Urbana-Champaign, Urbana, IL.
M A McMichaelVeterinary Clinical Medicine, University of Illinois at Urbana-Champaign, Urbana, IL.ORCID http://orcid.org/0000-0001-7959-4697
K S SwansonVeterinary Clinical Medicine, University of Illinois at Urbana-Champaign, Urbana, IL.
D A WilliamsVeterinary Clinical Medicine, University of Illinois at Urbana-Champaign, Urbana, IL.
University of Illinois Urbana-Champaign · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gastrointestinal microbiome is a diverse consortium of bacteria, archaea, fungi, protozoa, and viruses that inhabit the gut of all mammals. Studies in humans and other mammals have implicated the microbiome in a range of physiologic processes that are vital to host health including energy homeostasis, metabolism, gut epithelial health, immunologic activity, and neurobehavioral development. The microbial genome confers metabolic capabilities exceeding those of the host organism alone, making the gut microbiome an active participant in host physiology. Recent advances in DNA sequencing technology and computational biology have revolutionized the field of microbiomics, permitting mechanistic evaluation of the relationships between an animal and its microbial symbionts. Changes in the gastrointestinal microbiome are associated with diseases in humans and animals including inflammatory bowel disease, asthma, obesity, metabolic syndrome, cardiovascular disease, immune-mediated conditions, and neurodevelopmental conditions such as autism spectrum disorder. While there remains a paucity of data regarding the intestinal microbiome in small animals, recent studies have helped to characterize its role in host animal health and associated disease states. This review is intended to familiarize small animal veterinarians with recent advances in the field of microbiomics and to prime them for a future in which diagnostic tests and therapies will incorporate these developments into clinical practice.

Indexed as

Gastrointestinal MicrobiomeAnimalsDysbiosisMammalsMetabolomicsMetagenomicsMetagenomicsMicrobiomicsMicrobiotaPrebioticsProbiotics

Identifiers

PMID29171095
PMCPMC5787212
OpenAlexW2769629043

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.