Evidence map›Paper›PMID 29170942›Full record

ArticleJournal of autism and developmental disorders2018

Refractive Status and Amblyopia Risk Factors in Chinese Children with Autism Spectrum Disorder.

Jiaxing Wang, Gang Ding, Ying Li, Ning Hua, Nan Wei, Xiaoli Qi, Yuxian Ning, Ying Zhang, Xue Li, Jing Li and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Convergent genetic pathways linking neuropsychiatric and ocular disorders in children.Journal of child psychology and psychiatry, and allied disciplines · 2026
    Article
  3. Visual function and autism spectrum disorder.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Observational
  8. Article
  9. Strabismus in Genetic Syndromes: A Review.Clinical & experimental ophthalmology · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Ophthalmological findings in children with autism spectrum disorder.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
    Article
  16. Article
  17. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Jiaxing WangDepartment of Ophthalmology, Tianjin Medical University General Hospital, Tianjin, China.
Gang DingDepartment of Strabismus and Pediatric Ophthalmology, Tianjin Medical University Eye Hospital, Tianjin, 300384, China.
Ying LiDepartment of Ophthalmology, Emory University, Atlanta, GA, USA.
Ning HuaDepartment of Strabismus and Pediatric Ophthalmology, Tianjin Medical University Eye Hospital, Tianjin, 300384, China.
Nan WeiDepartment of Strabismus and Pediatric Ophthalmology, Tianjin Medical University Eye Hospital, Tianjin, 300384, China.
Xiaoli QiDepartment of Strabismus and Pediatric Ophthalmology, Tianjin Medical University Eye Hospital, Tianjin, 300384, China.
Yuxian NingDepartment of Strabismus and Pediatric Ophthalmology, Tianjin Medical University Eye Hospital, Tianjin, 300384, China.
Ying ZhangDepartment of Strabismus and Pediatric Ophthalmology, Tianjin Medical University Eye Hospital, Tianjin, 300384, China.
Xue LiDepartment of Strabismus and Pediatric Ophthalmology, Tianjin Medical University Eye Hospital, Tianjin, 300384, China.
Jing LiDepartment of Strabismus and Pediatric Ophthalmology, Tianjin Medical University Eye Hospital, Tianjin, 300384, China.
Linlin SongDepartment of Strabismus and Pediatric Ophthalmology, Tianjin Medical University Eye Hospital, Tianjin, 300384, China.
Xuehan QianDepartment of Strabismus and Pediatric Ophthalmology, Tianjin Medical University Eye Hospital, Tianjin, 300384, China. qianxuehan@yahoo.com.
Tianjin Medical University · CNTianjin Medical University Eye Hospital · CNEmory University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amblyopia risk factors in children with autism spectrum disorders (ASD) are usually hard to detect in early childhood due to poor cooperation and has not been reported in the Chinese population. We screened 168 Chinese children with ASD, aged between 3 and 8 years, and 264 age-matched neurotypical children with Spot photoscreener and basic ophthalmologic examinations. Children with ASD were found to have normal refractive status but significantly higher incidence of strabismus (16.1%), compared with control children (1.5%) (p < 0.01). Most of the cases of strabismus found in children with ASD were classified as esodeviation. Strabismus in children with ASD should be considered more seriously as an amblyopia risk factor by ophthalmologists and other healthcare professionals.

Indexed as

AmblyopiaAutism Spectrum DisorderChildChild, PreschoolChinaFemaleHumansMalePhysical ExaminationRisk FactorsStrabismusVision TestsAmblyopiaAutismChildrenRefractive statusRisk factorStrabismus

Identifiers

PMID29170942
OpenAlexW2768556997

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.