Evidence map›Paper›PMID 29170805›Full record

ArticleCurrent genetics2018

Role of actin depolymerizing factor cofilin in Aspergillus fumigatus oxidative stress response and pathogenesis.

Xiaodong Jia, Xi Zhang, Yingsong Hu, Mandong Hu, Shuguang Tian, Xuelin Han, Yansong Sun, Li Han

Abstract read
PubMed Publisher
In one paragraph

Article in Current genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Frontiers in fungal biology · 2022
    Review
  3. Virulence · 2021
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xiaodong JiaInstitute for Disease Control and Prevention of PLA, Academy of Military Medical Sciences, 20# Dongda Str., 100071, Beijing, China.
Xi ZhangInstitute for Disease Control and Prevention of PLA, Academy of Military Medical Sciences, 20# Dongda Str., 100071, Beijing, China.
Yingsong HuInstitute for Disease Control and Prevention of PLA, Academy of Military Medical Sciences, 20# Dongda Str., 100071, Beijing, China.
Mandong HuInstitute for Disease Control and Prevention of PLA, Academy of Military Medical Sciences, 20# Dongda Str., 100071, Beijing, China.
Shuguang TianInstitute for Disease Control and Prevention of PLA, Academy of Military Medical Sciences, 20# Dongda Str., 100071, Beijing, China.
Xuelin HanInstitute for Disease Control and Prevention of PLA, Academy of Military Medical Sciences, 20# Dongda Str., 100071, Beijing, China.
Yansong SunInstitute for Disease Control and Prevention of PLA, Academy of Military Medical Sciences, 20# Dongda Str., 100071, Beijing, China. sunys1964@hotmail.com.
Li HanInstitute for Disease Control and Prevention of PLA, Academy of Military Medical Sciences, 20# Dongda Str., 100071, Beijing, China. hanlicdc@163.com.ORCID http://orcid.org/0000-0001-9013-8414
Academy of Military Medical Sciences · CN

Funding

973 Program 2013CB531606the National Natural Science Foundation of China 31400134the National Natural Science Foundation of China 81273230
6 · The paper itself

Abstract

Aspergillus fumigatus is a major fungal pathogen that is responsible for approximately 90% of human aspergillosis. Cofilin is an actin depolymerizing factor that plays crucial roles in multiple cellular functions in many organisms. However, the functions of cofilin in A. fumigatus are still unknown. In this study, we constructed an A. fumigatus strain overexpressing cofilin (cofilin OE). The cofilin OE strain displayed a slightly different growth phenotype, significantly increased resistance against H

Indexed as

Oxidative StressA549 CellsActin Depolymerizing FactorsActinsAspergillus fumigatusBlotting, WesternCell WallEndocytosisHumansHydrogen PeroxideInflammation MediatorsInterleukin-8Monocyte Chemoattractant ProteinsPolymerizationPolysaccharidesReal-Time Polymerase Chain ReactionActin Depolymerizing FactorsActinsHydrogen PeroxideInflammation MediatorsInterleukin-8Monocyte Chemoattractant ProteinsPolysaccharidesTumor Necrosis Factor-alphaAspergillus fumigatusCell wall polysaccharidesCofilinInflammatory responseOxidative stress resistance

Identifiers

PMID29170805
OpenAlexW2769366134

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.