ArticleFrontiers in endocrinology2017
The Association of Thyroid Disease and Oral Lichen Planus: A Literature Review and Meta-analysis.
Article in Frontiers in endocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06550154 (Association Between Oral Lichen Planus and Thyroid Disease), which is not on this map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Association Between Oral Lichen Planus and Thyroid Disease: A Cross-sectional Study
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review of the role of interleukin inhibitors in lichen planus: therapeutic and paradoxical effects.Inflammopharmacology · 2025Pooled it
- Depression, anxiety, and stress in oral lichen planus: a systematic review and meta-analysis.Clinical oral investigations · 2022Pooled it
- The Relationship Between Lichen Planus and Thyroid Disorders in an Iranian Population: A Case-Control Study.Health science reports · 2026Article
- Clinicopathological characteristics and follow-up outcomes of patients with oral potentially malignant disorders: A 7-year observational cohort study.Scientific reports · 2026Observational
- Systemic Disease Associations of Oral Lichenoid Disease: A Retrospective Case-Control Study.Oral diseases · 2026Article
- Observational
- Article
- A case of erosive oral lichen planus in a child affected by β-Thalassemia after 5 years from bone marrow transplantation.BMC oral health · 2025Article
- Immune-Molecular Link between Thyroid and Skin Autoimmune Diseases: A Narrative Review.Journal of clinical medicine · 2024Review
- Oral and non-oral lichen planus show genetic heterogeneity and differential risk for autoimmune disease and oral cancer.American journal of human genetics · 2024Article
- The effect of antiresorptive therapy on the prevalence and severity of oral lichen planus: a retrospective study.BMC oral health · 2024Article
- The Correlation between Oral Lichen Planus and Thyroid Pathologies: A Retrospective Study in a Sample of Italian Population.European journal of dentistry · 2024Article
- Crossroads between Skin and Endocrine Glands: The Interplay of Lichen Planus with Thyroid Anomalies.Biomedicines · 2023Review
- Non-Coding RNAs as Potential Targets for Diagnosis and Treatment of Oral Lichen Planus: A Narrative Review.Biomolecules · 2023Review
- Reduction in Gingival Bleeding after Atelocollagen Injection in Patients with Hashimoto's Disease-A Pilot Study.International journal of environmental research and public health · 2023Article
- Lichen planus in Germany - epidemiology, treatment, and comorbidity. A retrospective claims data analysis.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2022Observational
- Immune mechanisms involved in the coexistence of oral lichen planus and autoimmune thyroid diseases.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2021Article
- Lichen Planus.Frontiers in medicine · 2021Review
- Possible Mechanisms Involved in the Cooccurrence of Oral Lichen Planus and Hashimoto's Thyroiditis.Mediators of inflammation · 2020Review
- Immune-mediated Skin Disorders and their Oral Manifestations in the Omani Population: A Hospital-based Study.Oman medical journal · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe objective of this study was to systemically evaluate the association between oral lichen planus (OLP) and thyroid disease.
methodEleven electronic databases were searched for any clinical study published up until August 2016 that explored an association between OLP and thyroid disease, complemented with manual searching. The titles and abstracts of all studies identified from the electronic searches were then assessed independently to determine inclusion of the study. The population of interest was patients with OLP, and the exposure was the presence of thyroid disease in OLP patients. Statistical analyses were conducted using Review Manager 5.2. The odds ratios (OR) and 95% confidence intervals (CIs) were calculated to evaluate the association between OLP and thyroid disease.
resultsEight studies were included for review, and of these, four case-control studies were included in the final meta-analysis. The mean Newcastle-Ottawa Scale score evaluating the methodological quality of the four studies was 6.5. The OR was 2.10 (95% CI: 1.47-3.01), indicating a statistically significant difference in the prevalence of thyroid disease between the OLP and control groups. Heterogeneity was satisfactory (
conclusionThis meta-analysis indicated a significantly high prevalence of thyroid disease among OLP patients compared with controls, suggesting that routine screening for thyroid disease could be beneficial to OLP patients. However, due to the small number of studies included, further studies are needed to confirm the results.
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