Evidence map›Paper›PMID 29170520›Full record

ArticleScientific reports2017

Integrated Proteomic and Metabolomic prediction of Term Preeclampsia.

Ray Bahado-Singh, Liona C Poon, Ali Yilmaz, Argyro Syngelaki, Onur Turkoglu, Praveen Kumar, Joseph Kirma, Matthew Allos, Veronica Accurti, Jiansheng Li and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Pathophysiological mechanisms in severe preeclampsia: role of upregulated proteins in blood pressure, extracellular matrix and immunity.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025
    Article
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  11. Advances in proteomic profiling of pediatric kidney diseases.Pediatric nephrology (Berlin, Germany) · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ray Bahado-SinghDepartment of Obstetrics and Gynecology, Beaumont Health, Royal Oak, MI, USA. Ray.bahado-singh@beaumont.org.
Liona C PoonHarris Birthright Research Centre for Fetal Medicine, King's College Hospital, London, UK.
Ali YilmazDepartment of Obstetrics and Gynecology, Beaumont Health, Royal Oak, MI, USA.
Argyro SyngelakiHarris Birthright Research Centre for Fetal Medicine, King's College Hospital, London, UK.
Onur TurkogluDepartment of Obstetrics and Gynecology, Beaumont Health, Royal Oak, MI, USA.
Praveen KumarDepartment of Obstetrics and Gynecology, Beaumont Health, Royal Oak, MI, USA.
Joseph KirmaOakland University, Rochester Hills, MI, USA.
Matthew AllosOakland University, Rochester Hills, MI, USA.
Veronica AccurtiHarris Birthright Research Centre for Fetal Medicine, King's College Hospital, London, UK.
Jiansheng LiHenan University of Chinese Medicine, Zhengzhou, Henan, China.
Peng ZhaoHenan University of Chinese Medicine, Zhengzhou, Henan, China.
Stewart F GrahamDepartment of Obstetrics and Gynecology, Beaumont Health, Royal Oak, MI, USA.ORCID 0000-0003-1001-0002
David R CoolDepartment of Pharmacology & Toxicology, Wright State University, Dayton, OH, USA.
Kypros NicolaidesHarris Birthright Research Centre for Fetal Medicine, King's College Hospital, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Term preeclampsia (tPE), ≥37 weeks, is the most common form of PE and the most difficult to predict. Little is known about its pathogenesis. This study aims to elucidate the pathogenesis and assess early prediction of tPE using serial integrated metabolomic and proteomic systems biology approaches. Serial first- (11-14 weeks) and third-trimester (30-34 weeks) serum samples were analyzed using targeted metabolomic (

Indexed as

AdultFemaleHumansMagnetic Resonance SpectroscopyMetabolomicsPre-EclampsiaPregnancyProteomicsROC CurveSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationTandem Mass Spectrometry

Identifiers

PMID29170520
PMCPMC5700929

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.