Evidence map›Paper›PMID 29170454›Full record

ArticleScientific reports2017

CB

M Hytti, S Andjelic, N Josifovska, N Piippo, E Korhonen, M Hawlina, K Kaarniranta, T J Nevalainen, G Petrovski, T Parkkari and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. The effects of cannabis and cannabinoids on the endocrine system.Reviews in endocrine & metabolic disorders · 2022
    Review
  9. Review
  10. Article
  11. Identification and biochemical analyses of selective CBEuropean journal of pharmacology · 2019
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

M HyttiSchool of Pharmacy, University of Eastern Finland, Kuopio, Finland. maria.hytti@uef.fi.
S AndjelicEye Hospital, University Medical Centre, Ljubljana, Slovenia.
N JosifovskaStem Cells and Eye Research Laboratory, Department of Ophthalmology, Faculty of Medicine, University of Szeged, Szeged, Hungary.
N PiippoSchool of Pharmacy, University of Eastern Finland, Kuopio, Finland.
E KorhonenSchool of Pharmacy, University of Eastern Finland, Kuopio, Finland.
M HawlinaEye Hospital, University Medical Centre, Ljubljana, Slovenia.
K KaarnirantaDepartment of Ophthalmology, School of Medicine, University of Eastern Finland, Kuopio, Finland.
T J NevalainenSchool of Pharmacy, University of Eastern Finland, Kuopio, Finland.
G PetrovskiStem Cells and Eye Research Laboratory, Department of Ophthalmology, Faculty of Medicine, University of Szeged, Szeged, Hungary.
T ParkkariSchool of Pharmacy, University of Eastern Finland, Kuopio, Finland.
A KauppinenSchool of Pharmacy, University of Eastern Finland, Kuopio, Finland.ORCID 0000-0001-8254-0200
University of Eastern Finland · FILjubljana University Medical Centre · SIOslo University Hospital · NOUniversity of Szeged · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A chronic low-level inflammation contributes to the pathogenesis of age-related macular degeneration (AMD), the most common cause of blindness in the elderly in Western countries. The loss of central vision results from attenuated maintenance of photoreceptors due to the degeneration of retinal pigment epithelium (RPE) cells beneath the photoreceptor layer. It has been proposed that pathologic inflammation initiated in RPE cells could be regulated by the activation of type 2 cannabinoid receptors (CB

Indexed as

CannabinoidsCell DeathCell LineHumansInflammationMacular DegenerationMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Oxidative StressReceptor, Cannabinoid, CB2Retinal Pigment EpitheliumSignal Transduction1,1-dimethylbutyl-1-deoxy-Delta(9)-THCCannabinoidsMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Receptor, Cannabinoid, CB2

Identifiers

PMID29170454
PMCPMC5701010
OpenAlexW2770566261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.