Evidence map›Paper›PMID 29170407›Full record

ArticleScientific reports2017

Higher risk sexual behaviour is associated with unawareness of HIV-positivity and lack of viral suppression - implications for Treatment as Prevention.

Helena Huerga, Emilie Venables, Jihane Ben-Farhat, Gilles van Cutsem, Tom Ellman, Chris Kenyon

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Helena HuergaClinical Research Department, Epicentre, Paris, France. helena.huerga@epicentre.msf.org.
Emilie VenablesSouthern African Medical Unit, Médecins Sans Frontières, Sans Frontières, South Africa.ORCID 0000-0002-6647-380X
Jihane Ben-FarhatClinical Research Department, Epicentre, Paris, France.
Gilles van CutsemSouthern African Medical Unit, Médecins Sans Frontières, Sans Frontières, South Africa.
Tom EllmanSouthern African Medical Unit, Médecins Sans Frontières, Sans Frontières, South Africa.
Chris KenyonHIV/STI Unit, Institute of Tropical Medicine, Antwerp, Belgium.ORCID 0000-0002-2557-8998
University of Cape Town · ZAEpicentre (South Africa) · ZAMédecins Sans Frontières · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Efficacy of Treatment as Prevention Strategy depends on a variety of factors including individuals' likelihood to test and initiate treatment, viral load and sexual behaviour. We tested the hypothesis that people with higher risk sexual behaviour are less likely to know their HIV-positive status and be virologically suppressed. A cross-sectional population-based survey of individuals aged 15-59 years old was conducted in 2013 in KwaZulu-Natal, South Africa. A two-stage cluster probability sampling was used. After adjustment for age and sex, lack of awareness of HIV-positivity was strongly associated with having more than one sexual partner in the preceding year (aOR: 2.1, 95%CI: 1.5-3.1). Inconsistent condom use was more common in individuals with more than one sexual partner (aOR: 16.6, 95%CI: 7.6-36.7) and those unaware (aOR: 3.7, 95%CI: 2.6-5.4). Among people aware of their HIV-positivity, higher risk sexual behaviour was associated with lack of viral suppression (aOR: 2.2, 95%CI: 1.1-4.5). Risky sexual behaviour seems associated with factors linked to poor health-seeking behaviour which may have negative implications for HIV testing and Treatment as Prevention. Innovative strategies, driven by improved epidemiological and anthropological understanding, are needed to enable comprehensive approaches to HIV prevention.

Indexed as

AdolescentAdultCross-Sectional StudiesFemaleHIV InfectionsHIV SeropositivityHumansMaleMass ScreeningMiddle AgedSexual BehaviorSexual PartnersSouth AfricaViral LoadYoung Adult

Identifiers

PMID29170407
PMCPMC5700952
OpenAlexW2768503698

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.