Evidence map›Paper›PMID 29170270›Full record

ArticleAJNR. American journal of neuroradiology2018

The Role of Hemodynamics in Intracranial Bifurcation Arteries after Aneurysm Treatment with Flow-Diverter Stents.

A P Narata, F S de Moura, I Larrabide, C M Perrault, F Patat, R Bibi, S Velasco, A-C Januel, C Cognard, R Chapot and 3 more

2 registry-linked trialsAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07707076 narecruitingnot on this mapstarted 2026, after this paper: background citation

Traditional Approach Versus Flow Diverter for Unruptured Intracranial Wide-neck Bifurcation Aneurysms: a Prospective International Multicenter Randomized Controlled Study (FD-BWA Study)

TypeinterventionalSponsorNanfang Hospital, Southern Medical UniversityRan2026 to 2030Enrolled266ConditionsUnruptured Intracranial Wide-neck Bifurcation AneurysmsArmsFlow Diverter Group, Stent Assisted Coiling Group
NCT07754188 recruitingnot on this mapstarted 2026, after this paper: background citation

Early Complications After Flow Diverter Versus Stent-Assisted Coiling for Unruptured Wide-Neck Intracranial Bifurcation Aneurysms: A Prospective Real-World Cohort Study

Typeobservational_patient_registrySponsorNanfang Hospital, Southern Medical UniversityRan2026 to 2028Enrolled274ConditionsUnruptured Intracranial Aneurysm, Intracranial Bifurcation Aneurysm, Wide-Neck AneurysmArmsFlow Diverter, Stent-Assisted Coiling
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

A P NarataFrom the University Hospital of Tours (A.P.N., R.B.), Tours, France ana-paula.narata@chu-tours.fr.ORCID 0000-0001-5658-1439
F S de MouraEngineering, Modeling, and Applied Social Sciences Center (F.S.d.M.), Federal University of ABC, Santo André, Brazil.ORCID 0000-0002-0433-1224
I LarrabidePLADEMA-CONICET (I.L.), Universidad Nacional del Centro de la Provincia de Buenos Aires, Tandil, Argentina.ORCID 0000-0002-7745-1964
C M PerraultMechanical Engineering Department, INSIGNEO Institute for in Silico Medicine (C.M.P., A.M.), University of Sheffield, Sheffield, United Kingdom.ORCID 0000-0003-2230-6994
F PatatUMR "Imagerie et Cerveau," Inserm U930 (F.P., A.B., C.A.S.), Université Francois Rabelais, Tours, France.ORCID 0000-0001-9347-750X
R BibiFrom the University Hospital of Tours (A.P.N., R.B.), Tours, France.ORCID 0000-0002-5189-3676
S VelascoUniversity Hospital of Poitiers (S.V.), Poitiers, France.ORCID 0000-0002-3120-487X
A-C JanuelUniversity Hospital of Toulouse (A.-C.J., C.C.), Toulouse, France.ORCID 0000-0003-4910-6386
C CognardUniversity Hospital of Toulouse (A.-C.J., C.C.), Toulouse, France.ORCID 0000-0003-4287-2627
R ChapotAlfried Krupp Krankenhaus (R.C.), Essen, Germany.ORCID 0000-0002-9245-0636
A BouakazUMR "Imagerie et Cerveau," Inserm U930 (F.P., A.B., C.A.S.), Université Francois Rabelais, Tours, France.ORCID 0000-0001-5709-7120
C A SennogaUMR "Imagerie et Cerveau," Inserm U930 (F.P., A.B., C.A.S.), Université Francois Rabelais, Tours, France.ORCID 0000-0001-5530-363X
A MarzoMechanical Engineering Department, INSIGNEO Institute for in Silico Medicine (C.M.P., A.M.), University of Sheffield, Sheffield, United Kingdom.ORCID 0000-0002-6702-7932

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeTreatment of intracranial bifurcation aneurysms with flow-diverter stents can lead to caliber changes of the distal vessels in a subacute phase. This study aims to evaluate whether local anatomy and flow disruption induced by flow-diverter stents are associated with vessel caliber changes in intracranial bifurcations. MATERIALS AND

methodsRadiologic images and demographic data were acquired for 25 patients with bifurcation aneurysms treated with flow-diverter stents. Whisker plots and Mann-Whitney rank sum tests were used to evaluate if anatomic data and caliber changes could be linked. Symmetry/asymmetry were defined as diameter ratio 1 = symmetric and diameter ratio <1 = asymmetric. Computational fluid dynamics was performed on idealized and patient-specific anatomies to evaluate flow changes induced by flow-diverter stents in the jailed vessel.

resultsStatistical analysis identified a marked correspondence between asymmetric bifurcation and caliber change. Symmetry ratios were lower for cases showing narrowing or subacute occlusion (medium daughter vessel diameter ratio = 0.59) compared with cases with posttreatment caliber conservation (medium daughter vessel diameter ratio = 0.95). Computational fluid dynamics analysis in idealized and patient-specific anatomies showed that wall shear stress in the jailed vessel was more affected when flow-diverter stents were deployed in asymmetric bifurcations (diameter ratio <0.65) and less affected when deployed in symmetric anatomies (diameter ratio ∼1.00).

conclusionsAnatomic data analysis showed statistically significant correspondence between caliber changes and bifurcation asymmetry characterized by diameter ratio <0.7 (

Indexed as

Cerebrovascular CirculationAgedFemaleHemodynamicsHumansHydrodynamicsIntracranial AneurysmMaleMiddle AgedModels, CardiovascularStents

Identifiers

PMID29170270
PMCPMC7410576

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.