ArticleUltrasound in medicine & biology2018
Evaluating the Benefit of Elevated Acoustic Output in Harmonic Motion Estimation in Ultrasonic Shear Wave Elasticity Imaging.
Article in Ultrasound in medicine & biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Liver shear wave elastography using a mechanical index exceeding regulatory limits is safe and effective.Radiology advances · 2025Article
- Shear wave elastography primer for the abdominal radiologist.Abdominal radiology (New York) · 2025Review
- The Future Is Beyond Bright: The Evolving Role of Quantitative US for Fatty Liver Disease.Radiology · 2023Review
- Quantifying the Impact of Imaging Through Body Walls on Shear Wave Elasticity Measurements.Ultrasound in medicine & biology · 2023Article
- Liver fibrosis assessment: MR and US elastography.Abdominal radiology (New York) · 2022Review
- On the Relationship between Spatial Coherence and In Situ Pressure for Abdominal Imaging.Ultrasound in medicine & biology · 2021Article
- Quantifying the Effect of Abdominal Body Wall on In Situ Peak Rarefaction Pressure During Diagnostic Ultrasound Imaging.Ultrasound in medicine & biology · 2021Article
- Hydrophone Spatial Averaging Correction for Acoustic Exposure Measurements From Arrays-Part I: Theory and Impact on Diagnostic Safety Indexes.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021Article
- A direct comparison of natural and acoustic-radiation-force-induced cardiac mechanical waves.Scientific reports · 2020Article
- Preclinical Imaging Using Single Track Location Shear Wave Elastography: Monitoring the Progression of Murine Pancreatic Tumor Liver Metastasis In Vivo.IEEE transactions on medical imaging · 2020Article
- Production of acoustic radiation force using ultrasound: methods and applications.Expert review of medical devices · 2018Review
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Authors and funding
5 authors.
Funding
Abstract
Harmonic imaging techniques have been applied in ultrasonic elasticity imaging to obtain higher-quality tissue motion tracking data. However, harmonic tracking can be signal-to-noise ratio and penetration depth limited during clinical imaging, resulting in decreased yield of successful shear wave speed measurements. A logical approach is to increase the source pressure, but the in situ pressures used in diagnostic ultrasound have been subject to a de facto upper limit based on the Food and Drug Administration guideline for the mechanical index (MI <1.9). A recent American Institute of Ultrasound in Medicine report concluded that an in situ MI up to 4.0 could be warranted without concern for increased risk of cavitation in non-fetal tissues without gas bodies if there were a concurrent clinical benefit. This work evaluates the impact of using an elevated MI in harmonic motion tracking for hepatic shear wave elasticity imaging. The studies indicate that high-MI harmonic tracking increased shear wave speed estimation yield by 27% at a focal depth of 5 cm, with larger yield increase in more difficult-to-image patients. High-MI tracking improved harmonic tracking data quality by increasing the signal-to-noise ratio and decreasing jitter in the tissue motion data. We conclude that there is clinical benefit to use of elevated acoustic output in shear wave tracking, particularly in difficult-to-image patients.
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